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MS Paper Critiqued

Researchers are criticizing a paper linking a rare gene variant to multiple sclerosis, Stat News reports.

A Winthrop-University Hospital team showed that demethylated circulating cell-free DNA from dying oligodendrocytes is a biomarker for relapsing-remitting MS.

Certain bacterial species appear more common in gut microbiomes of individuals with MS, coinciding with inflammation-related gene expression in host blood.

Researchers uncovered four new multiple sclerosis susceptibility loci through a genome-wide association study, and linked them to epigenetic regulation.

The research team linked a mutation in a protein-coding gene to inherited multiple sclerosis and genetic risk factors for developing the disease. 

IQuity's current tests analyze gene expression patterns detected in mRNA, but the firm is also exploring the diagnostic potential of long non-coding RNAs.

The team said their approach may have several applications, including evaluation of cellular response to therapies, and early diagnosis of diseases like cancer.

With the help of a newly generated gene regulatory network for T-cell differentiation, researchers identified transcription factors with ties to disease symptoms.

Regulus said it was able to develop its miRNA extraction and profiling technology to meet the quality specifications set out by its partner.

DioGenix and its MSPrecise NGS test for multiple sclerosis will be merged into Amarantus as a foundational asset of a growing neuro-diagnostic business.

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In Genome Biology this week: comparative genomics study of Aspergillus, genetic variation in indigenous African cattle, and more.

Some people who harbor genetic variants associated with disease show no signs and may give insight into the continuum of symptoms, Spectrum reports.

Some 57 snow monkeys at a Japanese zoo were found to be rhesus macaque hybrids, which are banned in Japan.

British researchers say they've been removed from EU grant applications, according to the Guardian.