monogenic disease Preimplantation Genetic Testing Could be Informed by Whole-Genome Reconstruction, Study Shows Researchers demonstrated the potential for reconstructing variant patterns across the genomes of sibling embryos, using the data to estimate polygenic and monogenic disease risk. Sequencing of Newborns Does Not Create Negative Psychosocial Effect on Families, Study Finds The researchers also found that there was no lasting psychosocial harm among families who received a monogenic disease risk finding for their infant. GenCC Database Harmonizes Gene-Disease Relationships for Researchers Premium The Gene Curation Coalition, led by the Broad Institute, is serving as a clearinghouse of sorts for curated datasets on Mendelian disorders. International Commission Deems Germline Genome Editing Not Yet Safe in Human Embryos Premium The panel also said that if any nation does decide to allow germline genome editing, its use should be limi Sequencing Could Augment Other Newborn Screening Approaches, NC NEXUS Study Finds Sequencing-based newborn screening could not identify all children with metabolic disorders or hearing loss, but could interrogate a larger number of conditions. May 28, 2020 Mendelian Disease Diagnosis Gets Boost From Automated Software That Scans Full-Text Articles Premium May 7, 2020 Primary Immunodeficiency Study Highlights Monogenic, Common Variant Disease Contributors Jun 27, 2019 MedSeq Team Reports Genome Analysis, Reanalysis Results for 100 Participants Sep 26, 2018 GWAS Reveals Common, Polygenic Contributors to Neurodevelopmental Disorders Apr 12, 2018 ACMG Presenter Touts Literature Mining Tool for Ranking Monogenic Disease Candidates Oct 2, 2017 Clinical Exomes Contribute to Monogenic Disease Diagnoses in Infant ICU, Study Finds Jul 31, 2017 Genetic Testing Evaluated For Diagnosing Epilepsy, Monogenic Conditions Jul 28, 2017 Panel Sequencing Leads to Pathogenic Mutations in Autoinflammatory Cases Jun 19, 2017 New Monogenic Form of Severe Atopic Dermatitis Described Jun 16, 2017 Combining PGD and PGS to Select Embryos Increases Pregnancy Rate But Results in Fewer Transfers Premium Mar 24, 2017 ACMG Talk Highlights Importance of Detecting Rare, Monogenic Forms of Diabetes Oct 30, 2013 Genome Québec, Sainte-Justine Hospital Evaluating Tech for New Clinical Pediatric Sequencing Center Premium Jul 18, 2012 Children's Mercy Using HiSeq2500 'STAT-Seq' Method to Diagnose Monogenic Disorders in the NICU Premium Breaking News Canadian Healthcare Providers, Policymakers Value Different Aspects of Clinical Genomic Sequencing New Products Posted to GenomeWeb: Oxford Nanopore, Bio-Rad, NanoString, More People in the News at OraSure, Element Biosciences, Micronoma, More Guardant Health Files Motions to Dismiss, Change Venue in Illumina Patent Lawsuit In Brief This Week: SQI Diagnostics, T2 Biosystems, Enhanc3D, QuidelOrtho, More Illumina, Precision Health Research Singapore Partner for 100K Genomes Population Study The Scan Blend of Omicron With Delta The Associated Press reports that currently circulating Omicron variants have some features previously seen in the Delta variant. Limited Contrast The New York Times reports that there is a shortage of a contrast agent used for some medical scans. Pig Improvement Farmers in China are using genetics to improve their hog herds, according to Reuters. Science Papers Present Way to Molecularly Classify Prostate Cancer, Saliva-Based SARS-CoV-2 Test, More In Science this week: approach to molecularly classify prostate tumors, saliva-based test for SARS-CoV-2, and more.