mitochondrial disease Bacterial Toxin Leads to CRISPR-Free Mitochondrial DNA Base Editing Unlike previously described cytidine deaminases, Mitochondrial DNA Can Be Paternally Inherited in Humans, New Study Finds Researchers have uncovered three families in which individuals inherited mitochondrial DNA from their fathers, upending existing belief. Researchers Use ZFNs to Edit Mutation in Mitochondrial DNA In Vivo For the first time, researchers used mitochondrially targeted zinc-finger nucleases to induce specific elimination of mutant mtDNA across the heart. Genetic Testing Evaluated For Diagnosing Epilepsy, Monogenic Conditions A pair of new studies evaluated whole-exome sequencing and other genetic tests in children with epilepsy and in other undiagnosed monogenic disease cases. Courtagen, Astellas Partner on Mitochondrial Disease Drug Development Courtagen will use its ZiPhyr bioinformatics pipeline to help Astellas develop a predictive model that can be used in early-stage drug development. Aug 5, 2016 Three Newly Identified Mitochondrial Proteins May Play Role in Disease Aug 3, 2016 Newcastle University Lab Converts Sanger Tests to NGS Test for Mitochondrial Disorder Premium Mar 22, 2016 Tute Genomics, UNIConnect Ink Deal With Newborn Screening Ontario Sep 23, 2015 UAB Heads Partnership Focusing on Patient Care for Mitochondrial Diseases Jul 15, 2015 Courtagen Raises $20M Jun 17, 2015 Courtagen Raises $7.5M Apr 23, 2015 Courtagen Inks Distribution Deals for Israel, Thailand Apr 23, 2015 Salk Scientists Develop Method to Edit Mutations in Germline Mitochondrial DNA Premium Mar 25, 2014 Courtagen to Provide Genetic Profiling for Raptor's Mitochondrial Disorder Drug Trial Jul 30, 2012 Transgenomic Teams With MCW to Offer NGS Testing Services Mar 21, 2012 Baylor, Arup Turn to Next-Gen Sequencing to Address Challenges of Mitochondrial Disease Diagnosis Premium Feb 29, 2012 New Products: GeneDx's Mito101 Premium Oct 19, 2011 Dutch Study Aims to Demonstrate Cost-Effectiveness of Reimbursing for Exome Sequencing Dx Premium Jun 21, 2011 Transgenomic Launches NGS-Based Mitochondrial Disease Test, Developing Autism Risk Test Premium Apr 12, 2011 Medomics Raises Funds to Grow its Sequencing-Based Tests for Mitochondrial Disease Premium Sep 7, 2010 Gene Prediction and Targeted Sequencing Detect Causal Mutations in Complex Mitochondrial Disease Premium Mar 6, 2009 Transgenomic Gets California OK for Clinical Lab Feb 3, 2009 Transgenomic Licenses Power3 Neuro Biomarkers Breaking News Lander, Collins Offer Vision for Advanced Research Projects Agency for Health LetsGetChecked Partners With California Department of Public Health for COVID-19 Sequencing BTIG Initiates Coverage of Berkeley Lights With Buy Rating Quest Diagnostics to Offer Biocept's Target Selector NGS Lung Cancer Test Novacyt 2020 Revenues Surge on Strong Demand for SARS-CoV-2 Testing Products Leidos Wins CDC Bioinformatics Contract Worth up to $13M The Scan Could Cost Billions NBC News reports that the new Alzheimer's disease drug from Biogen could cost Medicare in the US billions of dollars. Not Quite Sent The Biden Administration likely won't meet its goal of sending 80 million SARS-CoV-2 vaccine doses abroad by the end of the month, according to the Washington Post. DTC Regulation Proposals A new report calls on UK policymakers to review direct-to-consumer genetic testing regulations, the Independent reports. PNAS Papers on Mosquito MicroRNAs, Acute Kidney Injury, Trichothiodystrophy In PNAS this week: microRNAs involved in Aedes aegypti reproduction, proximal tubule cell response to kidney injury, and more.