mitochondrial disease Omics AI Software Firm Standigm Eyes 2024 IPO, Partnerships With Major Cloud Providers Premium A month into a collaboration with Nashville Biosciences, the Korean company is looking for additional partnerships with research institutions and Big Pharma to accelerate target discovery. United Mitochondrial Disease Foundation, Reneo Pharmaceuticals Team up for Free Genetic Testing Certain patients with suspected primary mitochondrial diseases will be eligible for the panel, which sequences the mitochondrial genome and 320 nuclear genes. Researchers Achieve Targeted A-to-G Base Editing in Human Mitochondrial DNA Premium The technology can in principle correct almost half of pathogenic mtDNA mutations, paving the way for mitochondrial disease modeling and therapeutic applications. Mitochondrial Protein Resource Reveals New Disease Players Researchers developed a "mitochondrial orphan protein multi-omics" (MITOMICS) app by profiling proteins, lipids, and metabolites in cells lacking individual mitochondrial proteins. Free Mitochondrial Disease Genetic Testing Program Established by Zogenix, Others The patient-initiated program is available to anyone in the US suspected of having mitochondrial disease. Jul 8, 2020 Bacterial Toxin Leads to CRISPR-Free Mitochondrial DNA Base Editing Nov 27, 2018 Mitochondrial DNA Can Be Paternally Inherited in Humans, New Study Finds Sep 25, 2018 Researchers Use ZFNs to Edit Mutation in Mitochondrial DNA In Vivo Jul 31, 2017 Genetic Testing Evaluated For Diagnosing Epilepsy, Monogenic Conditions Sep 16, 2016 Courtagen, Astellas Partner on Mitochondrial Disease Drug Development Aug 5, 2016 Three Newly Identified Mitochondrial Proteins May Play Role in Disease Aug 3, 2016 Newcastle University Lab Converts Sanger Tests to NGS Test for Mitochondrial Disorder Premium Mar 22, 2016 Tute Genomics, UNIConnect Ink Deal With Newborn Screening Ontario Sep 23, 2015 UAB Heads Partnership Focusing on Patient Care for Mitochondrial Diseases Jul 15, 2015 Courtagen Raises $20M Jun 17, 2015 Courtagen Raises $7.5M Apr 23, 2015 Courtagen Inks Distribution Deals for Israel, Thailand Apr 23, 2015 Salk Scientists Develop Method to Edit Mutations in Germline Mitochondrial DNA Premium Mar 25, 2014 Courtagen to Provide Genetic Profiling for Raptor's Mitochondrial Disorder Drug Trial Jul 30, 2012 Transgenomic Teams With MCW to Offer NGS Testing Services Mar 21, 2012 Baylor, Arup Turn to Next-Gen Sequencing to Address Challenges of Mitochondrial Disease Diagnosis Premium Feb 29, 2012 New Products: GeneDx's Mito101 Premium Oct 19, 2011 Dutch Study Aims to Demonstrate Cost-Effectiveness of Reimbursing for Exome Sequencing Dx Premium Jun 21, 2011 Transgenomic Launches NGS-Based Mitochondrial Disease Test, Developing Autism Risk Test Premium Apr 12, 2011 Medomics Raises Funds to Grow its Sequencing-Based Tests for Mitochondrial Disease Premium Load More Breaking News Compact Gene Editing Enzyme May Improve Success Rates of Gene Therapies People in the News at Veracyte, Invitae, Mount Sinai, InterVenn Biosciences, Applied BioCode, More New Products Posted to GenomeWeb: Qiagen, IDT, Revvity, Mission Bio, NRichDx, More FDA Releases Proposed Rule for Oversight of Laboratory-Developed Tests CStone Pharmaceuticals, Genetron Companion Diagnostic Receives NMPA Approval The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.