mitochondrial disease

Researchers have uncovered three families in which individuals inherited mitochondrial DNA from their fathers, upending existing belief.

For the first time, researchers used mitochondrially targeted zinc-finger nucleases to induce specific elimination of mutant mtDNA across the heart.

UK regulators have approved the use of mitochondrial transfer in two cases, according to the Guardian.

The US Food and Drug Administration has sent a letter to a New York doctor, instructing him to stop marketing mitochondrial transfers, the Associated Press reports.

A pair of new studies evaluated whole-exome sequencing and other genetic tests in children with epilepsy and in other undiagnosed monogenic disease cases.

UK allows licenses for mitochondrial replacement therapy, Reuters reports.

More Babies Ahead

A fertility clinic in Mexico plans to perform additional mitochondrial replacement therapies next year, according to the New Scientist.

Ready for Transfers

Mitochondrial replacement therapy may soon be occurring in the UK, according to the Guardian.

New Baby Boy

New York-based doctors announce the birth of a baby boy whose parents underwent mitochondrial transfer therapy, New Scientist reports.

Courtagen will use its ZiPhyr bioinformatics pipeline to help Astellas develop a predictive model that can be used in early-stage drug development.

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An artificial intelligence-based analysis suggests a third group of ancient hominins likely interbred with human ancestors, according to Popular Mechanics.

In Science this week: reduction in bee phylogenetic diversity, and more.

The New York Times Magazine looks into paleogenomics and how it is revising what's know about human history, but also possibly ignoring lessons learned by archaeologists.

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.