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metastasis

Metastatic Tumor Subtypes Found With Expression Profiling

Researchers unearthed four metastatic tumor molecular subtypes based on gene expression profiles in patient-derived xenograft and human tumor samples.

Brain Metastases Analysis Points to Distinct Tumor Immune Microenvironments, Potential Treatments

Researchers conducted an immunogenomic analysis of brain metastases from individuals with primary lung or breast cancer.

Colorectal Cancer Lines Characterized With Top-Down Proteomics Approaches

Using several mass spec-based methods, researchers profiled protein and proteoform patterns in non-metastatic and metastatic colorectal cancer cell lines.

SkylineDx Gains CE-IVD Mark for Melanoma Metastasis Risk Assay

The Netherlands-based firm is partnering with Belgian company Biocartis on European commercialization of the qPCR assay, which could reduce unnecessary surgeries.

Treatment-Resistant Prostate Cancer Clues Drawn From Circulating Tumor DNA Dynamics

Deep genome sequencing on cell-free plasma DNA helped track tumor evolution and drug resistance features in metastatic, castration-resistant prostate cancers.

Jun 22, 2022

Plus Therapeutics, Biocept Ink Lab Services Agreement for ReSPECT-LM Trial

Feb 3, 2022

MSK Genomic Analysis Uncovers Features of Metastatic Cancer

Dec 21, 2021

Biocept to Refocus CNSide Assay Plans After FDA Feedback Suggests Targeting Narrower Indications
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Aug 16, 2021

Advanced Gastric Cancer Multiomic Analysis Reveals New Potential Therapeutic Targets

Aug 9, 2021

Single Metastatic Cancer Genome Analysis Appears Sufficient to ID Biomarkers, Treatment Options

Mar 31, 2021

Biocept Prepares for First FDA Foray With CSF Liquid Biopsy Brain Metastases Assay
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Mar 29, 2021

Biocept Q4 Revenues Spike as COVID-19 Testing Continues to Soar, Core Cancer Tests Lag

Feb 16, 2021

Circulating Tumor DNA Provides Prognostic Clues in Advanced BRAF-Mutated Melanoma Cases

Jan 4, 2021

Metastatic Gastric Cancer Outcomes Informed by Single-Cell Transcriptome Profiles

Nov 19, 2020

Exceptional Responders Cancer Study Points to Possible Treatment Targets
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Nov 13, 2020

Biocept Eyes Neuro-Oncology for Future Liquid Biopsy Growth as Testing Lags Amid COVID Pandemic
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Sep 22, 2020

Metastatic Cancer Treatment Markers Identified in Clinical WGS Study

Sep 4, 2020

Integrated Proteomic Study Leads to Metastasis, Response Clues in Chinese Colorectal Cancer Cases

Jul 20, 2020

Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift

Jul 13, 2020

Metastatic Prostate Cancer Methylation Analysis Reveals Subtype, Ties to Driver Genes

Jun 30, 2020

Foundation Medicine Shifts Focus to Early Cancer Detection With Lexent Bio Acquisition
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May 31, 2020

Oncologists Make Progress Toward Showing Utility for Brain Cancer Liquid Biopsy

May 18, 2020

Tumor Metastases Analysis Indicates Early Systemic Spread

Mar 23, 2020

Lung Cancer Brain Metastasis Genomes Marked by Recurrent Amplifications, Deletions

Oct 23, 2019

Metastatic Tumor Profiles Lead to Potential Treatment Targets

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The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.