meningitis

The prospective, multi-site clinical trial will evaluate the clinical utility of unbiased sequencing for identifying pathogens in suspected CNS infections.

The observational study showed delays to diagnosis reduced the chances of identifying pathogens and generally led to poorer outcomes.

BioGx now offers 11 CE-marked infectious disease tests that run on Becton Dickinson's BD Max platform.

The Dublin-based company also aims to raise up to €5 million this year to support additions to its R&D and sales and marketing teams.

A separate UCSF group has already begun implementing a different version of the metagenomic sequencing assay in the clinic.

The university's researchers have developed a laboratory test that measures the body's response to infection in the blood, and can distinguish between bacterial and viral meningitis.  

The test leverages loop mediated isothermal amplification technology and enables the rapid detection of Neisseria meningitidis directly from cerebrospinal fluid samples.

The Ultra's combination of a lower limit of detection and ability to find dead bacilli after starting TB therapy vastly improves sensitivity compared to other tests, the study’s authors said.

The loan from the European Investment Bank will go toward the development of Stat-Dx's diagnostic platform for detecting infectious pathogens, such as meningitis. 

At Tri-Con, UCSF's Charles Chiu discussed validation of a metagenomic NGS test as well as a new project to develop an RNA sequencing panel for Lyme disease.

Pages

Though many details have yet to be worked out, the draft deal for the UK's withdrawal from the EU is giving researchers some hints for what they can expect, Nature News says.

DNA testing has solved a 100-year-old mystery contained in the skull and teeth samples of a now-extinct monkey that once inhabited Jamaica, Gizmodo reports.

As the UN ponders a ban on gene drives, one malaria researcher says there are less dramatic ways to fight the disease in Africa than unleashing GM mosquitoes on a whole continent.

In Nature this week: an improved reference genome of the Aedes aegypti mosquito, genomes of four species of truffles, and more.