medulloblastoma Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy The study found certain patients did not benefit from lower doses of radiation therapy, suggesting the need for molecular selection. Cancer Researchers Discover Novel Inherited Mutation Predisposing Children to Medulloblastoma The researchers identified rare germline loss-of-function variants across the ELP1 gene in 14 percent of pediatric patients in a medulloblastoma subgroup. Medulloblastoma Single-Cell Study Yields Tumor-Initiating Cell Population Containing Outcome Clues A population of progenitor cells identified in mouse models of the Sonic Hedgehog medulloblastoma subtype led to a gene that is highly expressed in patients with poor outcomes. Medulloblastoma Molecular Subtypes Refined With Single-Cell Transcriptome Data Using single-cell RNA-seq and other approaches, researchers looked at the four known medulloblastoma subtypes and the brain cell types from which they arise. Pediatric Oncologists Employing Variety of Sequencing Strategies for Treatment, Research Premium Though some experts prefer the comprehensive nature of whole-genome sequencing, others find whole-exome sequencing or targeted exome panels to be more useful. May 10, 2018 New Medulloblastoma Predisposition Genes Result in Proposed Screening Guidelines Jul 19, 2017 Integrated Medulloblastoma Genomics Study Reveals Refined View of Tumor Subtypes Apr 10, 2017 Medulloblastoma Marked by Intra-Tumor Mutation Diversity Jan 28, 2016 International Team IDs Epigenetic Differences Between Medulloblastoma Subtypes Jan 13, 2016 Sequencing Study Reveals Substantial Mutational Changes in Medulloblastomas at Diagnosis, Relapse May 9, 2013 In Biology of Genomes Talk, Single-cell Analysis Offers Refined View of Medulloblastoma Jul 25, 2012 Studies Improve Characterization of Childhood Brain Cancer Subtypes Feb 15, 2012 Genome BC Funds $9.8M Project to Identify Subgroups in Medulloblastoma for Personalized Treatment Premium Feb 1, 2012 Genome BC Funds $9.8M Project to Sequence 1K Childhood Brain Tumors Premium Dec 16, 2010 International Team Reports on Genomic Analyses of Pediatric Brain Cancer Breaking News Bio-Rad Laboratories Q2 Revenues Climb 33 Percent, Beat Estimates Veracyte Q2 Revenues More Than Double on Test Volume Spike Increased Testing Revenues Boost Opko Health Q2 Revenues 47 Percent Qiagen Q2 Revenues Grow 28 Percent CareDx Q2 Revenues Up 77 Percent Secondary Genetic Findings Often Requested if Given Second Chance, Study Finds The Scan Booster Push New data shows a decline in SARS-CoV-2 vaccine efficacy over time, which the New York Times says Pfizer is using to argue its case for a booster, even as the lower efficacy remains high. With Help from Mr. Fluffington, PurrhD Cats could make good study animals for genetic research, the University of Missouri's Leslie Lyons tells the Atlantic. Man Charged With Threatening to Harm Fauci, Collins The Hill reports that Thomas Patrick Connally, Jr., was charged with making threats against federal officials. Nature Papers Present Approach to Find Natural Products, Method to ID Cancer Driver Mutations, More In Nature this week: combination of cryogenic electron microscopy with genome mining helps uncover natural products, driver mutations in cancer, and more.