medulloblastoma

This Week in Nature

In Nature this week: investigation into the genetics of medulloblastoma, and more.

With mutation, expression, and epigenetic features from hundreds of medulloblastoma tumors, researchers characterized key features of brain tumor subtypes.

A multi-region analysis of medulloblastoma and other tumor types highlighted the dramatic somatic alteration differences that can crop up within a single tumor.

The team also potentially identified the cells of origin for the most common medulloblastoma subtype, which could help develop novel therapeutics. 

Researchers have found that mutations present in medulloblastoma tumors at relapse differ substantially from those present at diagnosis.

COLD SPRING HARBOR, NY (GenomeWeb News) – Through whole-exome sequencing of single cells from a medulloblastoma tumor, researchers were able to identify distinct cancer cell types within the tumor that otherwise may have been overlooked, work presented by Stanford University's Sofia Kyriazopoulou

NEW YORK (GenomeWeb News) – Three genomic studies published in Nature this week are expanding understanding of the mutations and structural variations that define the four subtypes of medulloblastoma, a childhood brain cancer.

The Hospital for Sick Children and the Michael Smith Genome Sciences Center are conducting a whole-genome sequencing study of 1,000 pediatric brain cancer tumors.

Using a combination of exome sequencing and microarray-based copy number analyses, researchers have identified mutations involved in a type of pediatric brain cancer called medulloblastoma.

A new analysis examines the gender gap among paper authors in the sciences and says it may take decades or more to close.

Researchers have uncovered signals of selection that may enable the Bajau people to free five hundreds of feet deep, Reuters reports.

In Science this week: paternally inherited cis-regulatory structural variants in autism, and more.

A new report outlines issues facing the implementation of personalized medicine in the UK, the Independent reports.