medulloblastoma

This Week in Nature

In Nature this week: investigation into the genetics of medulloblastoma, and more.

With mutation, expression, and epigenetic features from hundreds of medulloblastoma tumors, researchers characterized key features of brain tumor subtypes.

A multi-region analysis of medulloblastoma and other tumor types highlighted the dramatic somatic alteration differences that can crop up within a single tumor.

The team also potentially identified the cells of origin for the most common medulloblastoma subtype, which could help develop novel therapeutics. 

Researchers have found that mutations present in medulloblastoma tumors at relapse differ substantially from those present at diagnosis.

COLD SPRING HARBOR, NY (GenomeWeb News) – Through whole-exome sequencing of single cells from a medulloblastoma tumor, researchers were able to identify distinct cancer cell types within the tumor that otherwise may have been overlooked, work presented by Stanford University's Sofia Kyriazopoulou

NEW YORK (GenomeWeb News) – Three genomic studies published in Nature this week are expanding understanding of the mutations and structural variations that define the four subtypes of medulloblastoma, a childhood brain cancer.

The Hospital for Sick Children and the Michael Smith Genome Sciences Center are conducting a whole-genome sequencing study of 1,000 pediatric brain cancer tumors.

Using a combination of exome sequencing and microarray-based copy number analyses, researchers have identified mutations involved in a type of pediatric brain cancer called medulloblastoma.

A phylogenetic analysis indicates two venomous Australian spiders are more closely related than thought, the International Business Times reports.

Technology Review reports that 2017 was the year of consumer genetic testing and that it could spur new analysis companies.

In Science this week: CRISPR-based approach for recording cellular events, and more.

A new company says it will analyze customers' genes to find them a suitable date, though Smithsonian magazine says the science behind it might be shaky.