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Sequencing and other experiments on barcoded Plasmodium berghei mutant strains helped researchers narrow in on key metabolic pathways in the parasite's liver stage.
Two new grants are helping the company develop its SHERLOCK and INSPECTR technologies as the basis for creating innovative diagnostics.
In PLOS this week: genome-wide association study of non-syndromic orofacial cleft subtypes, epigenetic and transcriptomic analysis of pancreatic ductal adenocarcinoma, and more.
In Genome Biology this week: analysis of colorectal cancer progression, secretion system used by Vibrio cholerae, and more.
In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.
Single-cell transcriptomic profiles for more than 1,700 malaria-causing Plasmodium berghei parasites revealed gene expression patterns that differ by parasite stage.
In Genome Research this week: copy number variant analysis of Anopheles gambiae, comparison of approaches to predict transcription factor activity, and more.
The test uses unique PCR chemistries as well as a streamlined sample prep method to detect resistance mutations without DNA extraction.
Researchers have genetically modified a fungus to kill malaria-spreading mosquitos, according to NPR.
In PLOS this week: exome sequencing ties PIK3C2A mutation to new Mendelian disorder, genetic profiles of Plasmodium species in Namibia, and more.
A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.
Nature News writes that viral genomic surveillance in the US faces systemic issues.
President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.
In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.