Using a method that relied on Affymetrix arrays, researchers found that 38 patients in the trial had gene expression indicating they were in the ABC subtype.
The team found mutations in 17 genes involved in T cell activation and apoptosis, chromatin remodeling, the nuclear factor kappa beta pathway, and DNA damage response.
Clinicians at the recent ASCO noted that more practical and accurate molecular diagnostics are approaching the clinic alongside novel targeted drug regimens.
Researchers from the US and Italy identified relapse-related methylation profiles in diffuse large B-cell lymphoma tumors taken at diagnosis and relapse.
Direct-to-consumer genetic testing companies are searching for a genetic reason for why some people, but not others, become gravely ill with COVID-19, the Detroit Free Press reports.
In PNAS this week: forward genetics-base analysis of retinal development, interactions of T cell receptors with neoantigens in colorectal cancer, and more.
