Prospective research suggests DNA and RNA sequencing can reveal pathogen, microbiome, and host expression features to detect lower respiratory tract infections.
Single-cell RNA sequencing from mouse trachea and human bronchial epithelial cells unearthed new cell types, including ionocytes enriched for CFTR expression.
This year's winners of the Intel Talent Search developed software to help in drug development, a smartphone-based tool to detect lung disease, and more.
The group hopes to find biomarkers as a first step toward identifying or developing targeted therapeutics to avoid serious and life threatening outcomes of early lung disease in these newborns.
Data for tens of thousands of UK Biobank participants revealed an overlapping set of variants involved in airflow obstruction in heavy and never smokers.
In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.
