Lung Cancer
Molecular Clonal Tracking Method Captures Lung Cancer Treatment Response, Resistance Features
Using a single-cell sequencing and clonal fitness mapping method, researchers compared EGFR-mutant lung cancer cell responses to EGFR inhibition or targeted protein degradation.
FDA Approves Takeda's Exkivity With Thermo Fisher CDx for EGFR Exon20 Insertion-Positive NSCLC
This is the first time the FDA has approved a drug specifically for NSCLC patients who harbor rare EGFR Exon20 insertion mutations.
Lung Cancers in Non-Smokers Fall Into Informative Molecular Subtypes
Whole-genome sequencing of lung cancers in never smokers highlighted three copy number-based subtypes, along with alterations linked to patient outcomes.
Delfi Diagnostics Tags Lung Cancer as First Target for Fragmentation-Based Liquid Biopsy Tech
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Based on promising early results, the company is now conducting a larger case-control study to lock in a classifier for prospective validation in an intended-use population.
Through its real-world evidence registry, the firm hopes to further validate its NSCLC recurrence risk test as a tool for guiding adjuvant treatment.