lung adenocarcinoma

The team integrated tumor barcoding, genome editing, and ultra-deep barcode sequencing to interrogate pairwise combinations of tumor suppressor alterations.

This Week in PNAS

In PNAS this week: half-a-dozen Aspergillus sequenced, genetic similarities between friends and classmates, and more.

A new analysis hints that adenocarcinomas or squamous cell carcinomas may have certain overlapping expression patterns, regardless of the tissue of origin.

This Week in PNAS

In PNAS this week: effects of activating KRAS mutations in lung adenocarcinoma, stranded bisulfite sequencing method, and more.

The software takes somatic mutation profiles from individual patients as input and uses them to prioritize relevant mutations and potential treatments.

Exome sequences and copy number patterns suggest lung adenocarcinoma and squamous cell carcinoma are each marked by specific somatic mutations and driver genes.

The consortium will analyze data from patients and mouse models in the first year as part of efforts to find ways of detecting tumors earlier.

The firm presented data from a study that explored how the lung cancer gene expression test changes prognostic risk classifications compared to pathological factors.

In Genome Biology this week: intra-tumor heterogeneity assessed with single-cell RNA sequencing, common epigenetic alterations in tumors, and more.

In Genome Biology this week: investigation of host expression and microbial communities in pouchitis, liver fluke genome sequencing, and more.

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In an against-all-odds twist, a researcher studying exceeding rare FOXG1 mutations discovers her daughter has the syndrome.

An effort by Genomics Medicine Ireland is creating a database of diseases based on the genomics of people in Ireland. It now is looking into the possibility of including Scotland in its work.

In recent weeks, the direct-to-consumer genetics firm has rolled out a health hub where customers can share information concerning 18 common health conditions.

In PLOS this week, new genes associated with prostate cancer risk, genetic patterns in M. bovis, and more.