liver disease
Clonal Hematopoiesis of Indeterminate Potential Linked to Increased Risk of Chronic Liver Disease
A study of 214,563 individuals from four large cohorts shows CHIP is associated with an elevated risk of liver inflammation and chronic liver disease.
Beethoven's Genome Offers Clues to Composer's Liver Disease, Family History
Researchers analyzed DNA from authenticated hair samples of the German composer, identifying liver disease risk variants along with hepatitis B virus sequences.
Nonalcoholic Steatohepatitis Linked to Inflammation-Related Liver Cell Signature
Researchers uncovered a cell adhesion- and migration signature in a subset of NASH hepatocytes, along with expression of an inflammation-related EphB2 receptor tyrosine kinase.
Liver Disease Multiomic Analysis Reveals Detection Clues, Points to Treatment Strategies
Researchers found nonalcoholic fatty liver disease markers with a combination of genome-wide association analyses, blood gene expression profiling, and blood plasma proteomics.
Exome Sequencing Study Uncovers Rare Variants in Gene Protecting Against Liver Disease
The findings of the study, which was funded by Regeneron Pharmaceuticals, suggest a new treatment for conditions like nonalcoholic steatohepatitis (NASH).