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liver disease

GWAS Meta-Analysis Finds Five Genetic Loci Associated With Non-Alcoholic Fatty Liver Disease

In addition to the five disease susceptibility loci, the meta-analysis found a potentially causal effect of lower expression of the LPL gene in adipose tissue.

Chronic Liver Disease Genome Sequences Point to Recurrent Mutations in Metabolic Genes

Metabolic pathway mutations turned up across individuals and liver clones in non-alcoholic fatty liver disease or alcohol-related liver disease patients.

Second Genome, Virginia Commonwealth University Partner on NASH Biomarker Discovery

Second Genome aims to identify a composite biomarker for the noninvasive diagnosis of nonalcoholic steatohepatitis patients with advanced fibrosis.

Blood, Urine Biomarker Study Leads to Linked Loci, Disease-Related Risk Scores

By uncovering genetic factors behind blood and urine biomarkers, researchers came up with polygenic scores related to biomarker status and related disease risk.

Nonalcoholic Fatty Liver Disease Progression Can Be Traced by Gene Expression Signature

A transcriptomic study found 25 genes that are differentially expressed at various disease stages, suggesting the proteins they encode could serve as biomarkers.

Oct 20, 2020

Ymir Genomics Licenses Urine Biomarkers for Liver Disease Detection From OHSU

Apr 29, 2020

DiscernDx Acquires Luminist Labs

Feb 20, 2020

Namocell, Takara Bio, HepaTx Partner on Single-Cell Genomics for Late-Stage Liver Disease

Oct 23, 2019

Mutational Signatures Uncovered in Non-Cancerous Colon, Liver Tissue

Oct 9, 2019

Single-Cell Transcriptome Atlas Gives Peek at Cell Interactions in Liver Cirrhosis

Jul 10, 2019

Liver Cell Atlas Assembled From Single-Cell Transcriptome Data

Apr 15, 2019

Unexplained Liver Disease Cases Diagnosed by Exome Sequencing

Apr 9, 2019

Gut Microbiome Signature to Be Developed as Nonalcoholic Fatty Liver Disease Diagnostic
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Nov 1, 2018

ERS Genomics Licenses CRISPR Tech to DefiniGen for Human Cell Disease Models

Oct 30, 2018

Broad Institute Licenses CRISPR Technology to DefiniGen for Human Cell Disease Models

Jul 12, 2018

Early Efforts to Improve Drug-Induced Liver Injury Detection With Machine Learning Fall Short
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Jun 26, 2018

Liver Disease in Obese Women Linked to Gut Microbes, Metabolites

Mar 22, 2018

Researchers Find Gene Variant That Protects Against Chronic Liver Disease

May 18, 2017

MicroRNAs Could Serve as Biomarkers for Liver Impairment, Toxicity

May 16, 2017

Helena Biosciences, Ghent University Plan to Commercialize Liver Test

Apr 17, 2017

Bristol-Myers Squibb, Nordic Bioscience Collaborate on Nonalcoholic Fatty Liver Disease Biomarkers

Dec 19, 2016

Liver Disease GWAS Highlights Genetic Overlap With, Differences From IBD

Nov 17, 2016

Curable Launches Primary Sclerosing Cholangitis Genome Project

Apr 12, 2016

Intellia Files for $120M IPO, Inks Lucrative Collaboration With Regeneron

Apr 5, 2016

New Fish Virus Characterized in Genome Sequencing Study

Breaking News
The Scan

Taking Stock of the Stockpile

The US and European countries are evaluating their smallpox vaccine stockpiles as the number of monkeypox cases increases, the Washington Post reports.

Vitamin D From Tomatoes

According to Reuters, researchers in the UK have gene-edited tomatoes so their fruit contains vitamin D.

Cause Not Yet Spotted

NPR reports that a new study was unable to find a cause for persistent long COVID symptoms.

PNAS Papers on Central African Hunter-Gatherers, Myopia Development, Ancient Microtia Allele

In PNAS this week: population patterns among Central African hunter gatherers, effect of myopia-linked gene variant, and more.