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leukemia

Pharmacotyping Links Childhood Leukemia Subtypes to Treatment Response

With drug sensitivity and genomic profiles on acute lymphoblastic leukemia cells, coupled with patient data, researchers saw pharmacotypes related to treatment response and outcomes.

SeekIn Receives CE-IVD Mark for Leukemia Cancer Mutation Detection Kit

The company's PanCanSeek test uses whole-genome sequencing to analyze bone marrow samples from leukemia patients, replacing a variety of more targeted technologies.

Envisagenics, Cancer Research UK, Queen Mary University Collaborate on AML Drug R&D

Cold Spring Harbor spinout Envisagenics will apply its AI technology to multiomics data in pursuit of new therapies for acute myeloid leukemia and other hematopoietic cancers.

Polygenic Risk Score Shows Potential in Personalizing Chemotherapy for Pediatric AML Patients
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At ASH's annual meeting, researchers reported that patients with low scores on a 10-SNP test fared better when they got clofarabine plus the standard 7+3 course of chemo.

Aussie Variant Classification Effort Aims to Reduce Uncertainty in Hereditary Blood Cancer Diagnosis
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The researchers hope to determine whether tens of thousands of variants in RUNX1 and GATA2 increase predisposition to blood cancers.

Oct 26, 2022

Acute Myeloid Leukemia 3D Genome Analysis Uncovers Subtype-Specific Changes

Oct 24, 2022

Invivoscribe Files FDA Supplemental PMA for CDx Test to Select AML Patients for Daiichi Sankyo Drug

Oct 10, 2022

Computational Method Adds AML Clonal Resolution to Single-Cell RNA-seq Data
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Sep 1, 2022

Mission Bio Aims to Establish Proof of Concept for Single-Cell MRD Test in AML
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Aug 16, 2022

Invivoscribe, Kronos Bio Partner on Companion Diagnostic Test for Leukemia Drug

Aug 5, 2022

Chronic Lymphocytic Leukemia Genomic Study Reveals New Subtypes, Ties to Outcomes

Jul 28, 2022

Aniling Gets CE-IVD Marks for Cancer Sequencing Tests

Jul 6, 2022

New Approach Improves Estimating Cancer Risk From Age-Related Clonal Hematopoiesis

Jun 9, 2022

Sophia Genetics Teams With Spanish Diagnostics Firm, Institute on Chronic Lymphocytic Leukemia Care

May 26, 2022

Allogeneic Stem Cell Transplant Outcomes Improve With Diverse Gut Microbes, Immune Cells

May 19, 2022

ALL Genomes Marked by High DNA Methylation Levels

Apr 29, 2022

St. Jude Program Installing Nanopore Sequencing in Low-Income Countries to Diagnose Pediatric Blood Cancers
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Apr 26, 2022

Alercell to Distribute Zeesan Biotech Leukemia Fusion Gene Test Kit

Apr 21, 2022

Qlucore Hopes Pan-Cancer Classification Partnership Will Spur Growth in Precision Dx
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Apr 20, 2022

Proof-of-Principle Study Points to Possibility of Monitoring Pediatric ALL With Plasma Samples

Apr 19, 2022

Genetron Health Nabs CE Mark for Blood Cancer Residual Disease Test Kit

Apr 12, 2022

New Epigenomic Biomarker Could Predict CAR T-Cell Therapy Resistance in Advanced Childhood Leukemia
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Mar 3, 2022

AML Proteogenomic Study Points to Prognostic Proteomic Subtypes

Jan 27, 2022

Certain Childhood ALL Subtypes Linked to Genetic Ancestry

Dec 9, 2021

Rarecells Raises $13M in Series A Round to Develop Liquid Biopsy Early Cancer Detection Tests

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The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.