To explore the genetic basis of clonal hematopoiesis and its consequences, researchers analyzed genotyping data for more than 151,000 UK Biobank participants.
Researchers have found that the Btk-inhibitor ibrutinib, which is currently used to treat cancers that include types of lymphoma, could be effective in leukemia.
An international team of researchers compared genetic changes that occur in the blood of people who develop acute myeloid leukemia and those who do not.
Multi-Omics Factor Analysis looks for underlying causes of tumor variations by parsing and weighting genomic, epigenomic, transcriptomic, proteomic, and metabolomic data.
The companion diagnostic test identifies patients taking the Novartis drug Tasigna who are candidates for treatment-free remission monitoring.
Diagnostic WGS will be centralized and performed at the same Genomics England facility used in the 100,000 Genomes Project.
While digging into the tumor-suppressive mechanism for an X-linked gene called UTX, researchers found a similar protective role for the Y chromosome gene UTY.
The team searched for coding and noncoding elements involved in acquired resistance to cytarabine, the main treatment for acute myeloid leukemia.
St. Jude researchers found germline mutations in the transcription factor gene IKZF1 in 0.9 percent of presumed sporadic pediatric acute lymphoblastic leukemia cases.
The five-year-old firm recently completed a clinical trial of the real-time PCR-based test, called ProALL-BM, on patients from a European National Registry Study.
In a commentary at eLife, Brandeis University's Eve Marder calls on researchers to value and pursue truth.
Researchers have developed a way to quickly edit white blood cells, according to the New York Times.
In Science this week: rice gene enables plants to grow quickly in times of flooding, and more.
Education-linked genetic variants could also predict a small portion of a person's social mobility, Newsweek reports.