Ancient Leprosy Analysis Suggests High Pathogen Genetic Diversity in Medieval Europe
Dramatic genetic diversity in Mycobacterium leprae isolates from medieval Europe could point to a long history or potential origins on the continent.
Ancient DNA Analysis Indicates Certain HLA Allele Made Medieval Patients More Susceptible to Leprosy
A team of European researchers analyzed DNA from infected medieval skeletons to find the HLA allele DRB1*15:01 was more common among leprosy patients.
Leprosy Relapse, Reinfection Detected in Proof-of-Principle Sequencing Study
Following treated leprosy patients, researchers saw three cases of recurrence that were classified as re-infection or relapse cases with genome sequences.
Medieval Pilgrim Excavated in UK Carried Leprosy Strain That Still Circulates
Genetic analysis indicated that he was infected with a strain now found in south-central and western Asia.
Genome Sequencing Offers Clues to New Species of Leprosy-causing Bacterium
An international team sequenced the genome of Mycobacterium lepromatosis, the species behind diffuse lepromatous leprosy, or Lucio's leprosy.