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The study, led by researchers at OHSU, also identified a series of proteins linked to the Src signaling pathway that could prove useful in identifying renal cell carcinoma patients most likely to respond to treatment with Src inhibitors.

Biovista will use its Clinical Outcomes Search Space platform to identify new treatments as part of the EU's "p-medicine" project.

The agreement calls for the company to apply its mass spec-based phosphoproteomics platform to the study of cell signaling pathways targeted by UCB's therapeutic antibodies and to identify potential protein biomarkers linked to the drugs.

Through a two-stage genome-wide association study involving samples from nearly 20,000 individuals, an international research team has identified genetic loci associated with renal cell carcinoma, including SNPs in a known kidney cancer-related pathway.

With the assay, the Stanford researchers have begun examining protein phosphorylation levels in a variety of cancer types. The team has also entered into collaborations with several pharmaceutical firms to investigate the effects of therapeutic agents on protein phosphorylation levels in tumor cells.

In particular, George Mason University researcher Emanuel Petricoin expressed concerns about the project's plan to use samples from different patient cohorts for its discovery and verification stages.

The technology "has broad potential uses in the development of cancer prognostic assays including response predictions to therapeutics as well as research tools and reagents," PrognosDx said in a statement.

Imperial College London and its spinout DNA Electronics have created a prototype for the so-called SNP Dr., which is being developed under a £1.2 million project that also includes Pfizer.

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A UK study on mixing SARS-CoV-2 vaccines is expanding to include vaccines developed by additional companies, according to the Guardian.

According to Science, the US National Academy of Sciences is poised to eject two members accused of sexual harassment.

In Nucleic Acids Research this week: machine learning approach to detect DNA-bound proteins, CRISPR-based method for activating specific gene targets, and more.

The FDA and CDC call for a pause in administering Johnson & Johnson's SARS-CoV-2 vaccine while reports of rare blood clots are looked into, reports the Wall Street Journal.