kidney cancer Cancer Genome Analysis Unearths Potentially Targetable Tandem Repeat Expansions Investigators identified 160 recurrent repeat expansions in seven cancer types, including a kidney cancer-related expansion that appeared susceptible to a targeted treatment. ESHG: UK Study Finds 6 Percent of Renal Cell Carcinoma Patients Carry Cancer Risk Variant Researchers looked for pathogenic or likely pathogenic variants in 121 cancer risk genes in whole-genome sequencing data from 1,336 unselected RCC patients. Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases Researchers detected hereditary cancer susceptibility in around one-third of the Wilms tumor cases profiled in the Netherlands. Kidney Cancer Study Links Checkpoint Immunotherapy Responses to T Cell Features Researchers from the UK used integrated genomics to analyze prospectively collected samples from metastatic clear cell renal cell carcinoma patients. Macrophage Subpopulation May Predict Kidney Cancer Recurrence, Serve as Drug Target The macrophage population, which expressed higher levels of three genes, was enriched in tumors of patients who experienced recurrence after surgery. Apr 2, 2021 Allarity Therapeutics Seeks FDA Premarket Approval for Prediction Tool as CDx for Dovitinib Mar 30, 2021 Renal Cell Carcinoma Risk Gene Representation Can Vary With Ancestry Jan 5, 2021 Mutations in Mitochondrial DNA Underlie Certain Subtype of Aggressive Renal Cancer Jun 26, 2020 Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method Premium Apr 30, 2020 Treatment Clues Gleaned From Molecular Features in Rare Kidney Cancer Type Mar 11, 2020 Microbiome-Based Cancer Dx Emerges From Cancer Genome Atlas Reanalysis Dec 12, 2019 Proteomic Subtypes Identified in Pan-Cancer Analysis Nov 5, 2019 Somatic Copy Number Changes in Normal Tissues Near Tumors Shed Light on Oncogenic Processes Nov 1, 2019 Multi-Omic Kidney Cancer Analysis Identifies Subtypes for Stratifying Patients Sep 19, 2019 Celsius Therapeutics to Use Single-Cell Platform in Three New Immuno-Oncology Collaborations Aug 15, 2018 Natera Partners With Fox Chase to Evaluate ctDNA Cancer Assay Aug 9, 2018 Single-Cell Transcriptome Atlas Elucidates Features Shared by Cancerous, Normal Kidneys Jul 6, 2018 More Kidney Cancer Patients Have Hereditary Mutations Than Previously Thought Jun 15, 2018 PDL1 Amplifications Mark Subset of Solid Tumors, May Point to Checkpoint Blockade Response Jan 26, 2018 CanHelp Pushes Gene Expression Tests Toward Clinical Approval in China Premium Jan 4, 2018 Chromatin Remodeling Mutations Linked to Immunotherapy Response Nov 2, 2017 Gut Microbes May Contribute to Immunotherapy Response Aug 21, 2017 Genomic Analysis of Wilms Tumors Leads to Kidney Development-Related Pathways Jun 29, 2017 Genomic Health Kidney Cancer Test Gauges Recurrence Risk in Study, Not Benefit to Pfizer's Sutent Premium Apr 18, 2017 Boeing Grants ACS, HudsonAlpha, UAB $100K for Kidney Cancer Research Load More Breaking News Bio-Rad Laboratories, Cytek Biosciences Partner on Flow Cytometry Reagents Tecan Inks Deals for NGS Library Prep System With Element Biosciences, Singular Genomics Genomenon, Flagship Biosciences Partner on Biomarker Discovery, Companion Dx Development Velsera to Integrate Arima Genomics Gene Fusion Test in Pierian Clinical Platform Evonetix Raises $24M in Extended Series B Funding Round The Scan Study Points to Tuberculosis Protection by Gaucher Disease Mutation A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds. SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource. Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages. UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.