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kidney cancer

Cancer Genome Analysis Unearths Potentially Targetable Tandem Repeat Expansions

Investigators identified 160 recurrent repeat expansions in seven cancer types, including a kidney cancer-related expansion that appeared susceptible to a targeted treatment.

ESHG: UK Study Finds 6 Percent of Renal Cell Carcinoma Patients Carry Cancer Risk Variant

Researchers looked for pathogenic or likely pathogenic variants in 121 cancer risk genes in whole-genome sequencing data from 1,336 unselected RCC patients.

Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases

Researchers detected hereditary cancer susceptibility in around one-third of the Wilms tumor cases profiled in the Netherlands.

Kidney Cancer Study Links Checkpoint Immunotherapy Responses to T Cell Features

Researchers from the UK used integrated genomics to analyze prospectively collected samples from metastatic clear cell renal cell carcinoma patients.

Macrophage Subpopulation May Predict Kidney Cancer Recurrence, Serve as Drug Target

The macrophage population, which expressed higher levels of three genes, was enriched in tumors of patients who experienced recurrence after surgery.

Apr 2, 2021

Allarity Therapeutics Seeks FDA Premarket Approval for Prediction Tool as CDx for Dovitinib

Mar 30, 2021

Renal Cell Carcinoma Risk Gene Representation Can Vary With Ancestry

Jan 5, 2021

Mutations in Mitochondrial DNA Underlie Certain Subtype of Aggressive Renal Cancer

Jun 26, 2020

Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method
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Apr 30, 2020

Treatment Clues Gleaned From Molecular Features in Rare Kidney Cancer Type

Mar 11, 2020

Microbiome-Based Cancer Dx Emerges From Cancer Genome Atlas Reanalysis

Dec 12, 2019

Proteomic Subtypes Identified in Pan-Cancer Analysis

Nov 5, 2019

Somatic Copy Number Changes in Normal Tissues Near Tumors Shed Light on Oncogenic Processes

Nov 1, 2019

Multi-Omic Kidney Cancer Analysis Identifies Subtypes for Stratifying Patients

Sep 19, 2019

Celsius Therapeutics to Use Single-Cell Platform in Three New Immuno-Oncology Collaborations

Aug 15, 2018

Natera Partners With Fox Chase to Evaluate ctDNA Cancer Assay

Aug 9, 2018

Single-Cell Transcriptome Atlas Elucidates Features Shared by Cancerous, Normal Kidneys

Jul 6, 2018

More Kidney Cancer Patients Have Hereditary Mutations Than Previously Thought

Jun 15, 2018

PDL1 Amplifications Mark Subset of Solid Tumors, May Point to Checkpoint Blockade Response

Jan 26, 2018

CanHelp Pushes Gene Expression Tests Toward Clinical Approval in China
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Jan 4, 2018

Chromatin Remodeling Mutations Linked to Immunotherapy Response

Nov 2, 2017

Gut Microbes May Contribute to Immunotherapy Response

Aug 21, 2017

Genomic Analysis of Wilms Tumors Leads to Kidney Development-Related Pathways

Jun 29, 2017

Genomic Health Kidney Cancer Test Gauges Recurrence Risk in Study, Not Benefit to Pfizer's Sutent
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Apr 18, 2017

Boeing Grants ACS, HudsonAlpha, UAB $100K for Kidney Cancer Research

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The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.