kidney cancer Macrophage Subpopulation May Predict Kidney Cancer Recurrence, Serve as Drug Target The macrophage population, which expressed higher levels of three genes, was enriched in tumors of patients who experienced recurrence after surgery. Allarity Therapeutics Seeks FDA Premarket Approval for Prediction Tool as CDx for Dovitinib The DRP would be used to identify kidney cancer patients likely to benefit from dovitinib, a repurposed TKI for which Allarity plans to file an NDA this year. Renal Cell Carcinoma Risk Gene Representation Can Vary With Ancestry While risky variants in the FH gene were more common in renal cell carcinoma patients with African ancestry, European patients more often carried pathogenic CHEK2 gene changes. Mutations in Mitochondrial DNA Underlie Certain Subtype of Aggressive Renal Cancer The researchers said this new data could lead to the development of effective therapies for patients with hereditary leiomyomatosis and renal cell carcinoma. Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method Premium Investigators reported that methylation profiling could distinguish brain cancer subtypes and could detect kidney cancer with striking sensitivity in early experiments. Apr 30, 2020 Treatment Clues Gleaned From Molecular Features in Rare Kidney Cancer Type Mar 11, 2020 Microbiome-Based Cancer Dx Emerges From Cancer Genome Atlas Reanalysis Dec 12, 2019 Proteomic Subtypes Identified in Pan-Cancer Analysis Nov 5, 2019 Somatic Copy Number Changes in Normal Tissues Near Tumors Shed Light on Oncogenic Processes Nov 1, 2019 Multi-Omic Kidney Cancer Analysis Identifies Subtypes for Stratifying Patients Sep 19, 2019 Celsius Therapeutics to Use Single-Cell Platform in Three New Immuno-Oncology Collaborations Aug 15, 2018 Natera Partners With Fox Chase to Evaluate ctDNA Cancer Assay Aug 9, 2018 Single-Cell Transcriptome Atlas Elucidates Features Shared by Cancerous, Normal Kidneys Jul 6, 2018 More Kidney Cancer Patients Have Hereditary Mutations Than Previously Thought Jun 15, 2018 PDL1 Amplifications Mark Subset of Solid Tumors, May Point to Checkpoint Blockade Response Jan 26, 2018 CanHelp Pushes Gene Expression Tests Toward Clinical Approval in China Premium Jan 4, 2018 Chromatin Remodeling Mutations Linked to Immunotherapy Response Nov 2, 2017 Gut Microbes May Contribute to Immunotherapy Response Aug 21, 2017 Genomic Analysis of Wilms Tumors Leads to Kidney Development-Related Pathways Jun 29, 2017 Genomic Health Kidney Cancer Test Gauges Recurrence Risk in Study, Not Benefit to Pfizer's Sutent Premium Apr 18, 2017 Boeing Grants ACS, HudsonAlpha, UAB $100K for Kidney Cancer Research Mar 24, 2017 CancerLocator Tool Aims to Non-Invasively Diagnose Cancer, Pinpoint Tissue of Origin Aug 4, 2016 Checkpoint Blockade Response Shows Ties to Metabolic Gene Expression in Kidney Cancer Patients May 24, 2016 MDx Health Tightens Focus on Urology Space, Anticipates New Launches This Year Premium Apr 29, 2016 Fluxion Bioscience, UTHealth Collaborate on Liquid Biopsy Development Load More Breaking News Analysis Finds Sibling Cascade Testing Could Be Cost Effective in Pediatric Cancer Armonica Technologies Closes $2M Series B Financing Round Top Five Articles on GenomeWeb Last Week: SARS-CoV-2 PCR Tests; California Cancer Testing Law; More In Brief This Week: The Jackson Laboratory, CareDx, Merck Global Health Innovation Fund, and More People in the News: New Appointments at Grail, Foundation Medicine, Personalis, More New Products Posted to GenomeWeb: NanoString, Sophia Genetics, EliTech, Lybe Scientific, More The Scan J&J Booster Support A US Food and Drug Administration advisory panel has voted to support a booster dose of Johnson & Johnson's SARS-CoV-2 vaccine, according to the Los Angeles Times. To Keep the Cases Moving The president of the UK Royal College of Pathologists tells the Financial Times that more investment is needed to tackle a backlog of cases. NAS Expels Archaeologist Science reports Luis Jaime Castillo Butters' expulsion is the first of an international member from the US National Academy of Sciences. PLOS Papers on Angelman Syndrome-Like Cases, Salmonella Paratyphi A, SARS-CoV-2 in Brazil In PLOS this week: exome sequencing analysis of Angelman syndrome-like cases, genetic epidemiology of Salmonella Paratyphi A, and more.