kidney cancer Macrophage Subpopulation May Predict Kidney Cancer Recurrence, Serve as Drug Target The macrophage population, which expressed higher levels of three genes, was enriched in tumors of patients who experienced recurrence after surgery. Allarity Therapeutics Seeks FDA Premarket Approval for Prediction Tool as CDx for Dovitinib The DRP would be used to identify kidney cancer patients likely to benefit from dovitinib, a repurposed TKI for which Allarity plans to file an NDA this year. Renal Cell Carcinoma Risk Gene Representation Can Vary With Ancestry While risky variants in the FH gene were more common in renal cell carcinoma patients with African ancestry, European patients more often carried pathogenic CHEK2 gene changes. Mutations in Mitochondrial DNA Underlie Certain Subtype of Aggressive Renal Cancer The researchers said this new data could lead to the development of effective therapies for patients with hereditary leiomyomatosis and renal cell carcinoma. Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method Premium Investigators reported that methylation profiling could distinguish brain cancer subtypes and could detect kidney cancer with striking sensitivity in early experiments. Apr 30, 2020 Treatment Clues Gleaned From Molecular Features in Rare Kidney Cancer Type Mar 11, 2020 Microbiome-Based Cancer Dx Emerges From Cancer Genome Atlas Reanalysis Dec 12, 2019 Proteomic Subtypes Identified in Pan-Cancer Analysis Nov 5, 2019 Somatic Copy Number Changes in Normal Tissues Near Tumors Shed Light on Oncogenic Processes Nov 1, 2019 Multi-Omic Kidney Cancer Analysis Identifies Subtypes for Stratifying Patients Sep 19, 2019 Celsius Therapeutics to Use Single-Cell Platform in Three New Immuno-Oncology Collaborations Aug 15, 2018 Natera Partners With Fox Chase to Evaluate ctDNA Cancer Assay Aug 9, 2018 Single-Cell Transcriptome Atlas Elucidates Features Shared by Cancerous, Normal Kidneys Jul 6, 2018 More Kidney Cancer Patients Have Hereditary Mutations Than Previously Thought Jun 15, 2018 PDL1 Amplifications Mark Subset of Solid Tumors, May Point to Checkpoint Blockade Response Jan 26, 2018 CanHelp Pushes Gene Expression Tests Toward Clinical Approval in China Premium Jan 4, 2018 Chromatin Remodeling Mutations Linked to Immunotherapy Response Nov 2, 2017 Gut Microbes May Contribute to Immunotherapy Response Aug 21, 2017 Genomic Analysis of Wilms Tumors Leads to Kidney Development-Related Pathways Jun 29, 2017 Genomic Health Kidney Cancer Test Gauges Recurrence Risk in Study, Not Benefit to Pfizer's Sutent Premium Apr 18, 2017 Boeing Grants ACS, HudsonAlpha, UAB $100K for Kidney Cancer Research Mar 24, 2017 CancerLocator Tool Aims to Non-Invasively Diagnose Cancer, Pinpoint Tissue of Origin Aug 4, 2016 Checkpoint Blockade Response Shows Ties to Metabolic Gene Expression in Kidney Cancer Patients May 24, 2016 MDx Health Tightens Focus on Urology Space, Anticipates New Launches This Year Premium Apr 29, 2016 Fluxion Bioscience, UTHealth Collaborate on Liquid Biopsy Development Load More Breaking News Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study People in the News: New Appointments at Biocept, Novacyt, Centogene, Illumina, More In Brief This Week: Sophia Genetics, Twist Bioscience, Dante Labs, MGI, Codex DNA, More New Products Posted to GenomeWeb: SpeeDx, Bio-Techne, NuProbe, More DiaSorin Q2 Revenues Rise 20 Percent on SARS-CoV-2 Testing Demand Cepheid Gets $28M From BARDA for SARS-CoV-2 Tests The Scan Interfering With Invasive Mussels The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels. Participation Analysis A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports. Right Whales' Decline A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC. Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.