kidney cancer
Genomic Study Reveals Rearrangements Behind Female-Predominant Kidney Cancer
Researchers scoured dozens of tumor genome sequences to identify roles for active and inactive X chromosome sequences in Xp11 translocation renal cell carcinoma.
Kidney Cancer Genetic Contributors Emerge From Multiomic Study
Researchers uncovered genes associated with histological subtypes of renal cell carcinoma by integrating genetic, transcriptomic, and proteomic data.
Kidney Cancer Immunotherapy Response Linked to Signature Reflecting HLA, Tumor Immune Activity
Researchers found an immune checkpoint blockade response signature in renal cell carcinoma that reflects tumor immune activity influenced by human leukocyte antigen features.
Kidney Cancer Multiomics Study Reveals Subtypes, Suggests New Treatment Strategies
With genomic, transcriptomic, proteomic, and metabolomic profiling, researchers saw four clear cell renal cell carcinoma immune subtypes, one of which is linked to poor outcomes.
Rare Kidney Cancer Genomic Analysis Reveals Potential Target, Suggests Treatment
Investigators from the UK analyzed samples from two reninoma patients by whole-genome and RNA sequencing and found rearrangements of the NOTCH1 gene.