inflammatory disease
Inflammatory Arthritis Linked to Characteristic Gut Microbial Community Changes
With gut metagenomic sequencing on individuals with or without inflammatory arthritis, researchers flagged microbial taxa and pathways coinciding with disease types.
Rare Urinary Bladder Disease GWAS Points to Importance of Autoimmunity, Inflammation
A genome-wide association study for Hunner-type interstitial cystitis led to amino acid variants in the class II human leukocyte antigen DQ-beta1 and DP-beta1 chain genes.
Multisystem Inflammatory Syndrome in Children Linked to Rare, Immune-Related Variants
With exome sequences and clinical data for dozens of Middle Eastern or Asian children, researchers unearthed rare MIS-C-associated variants in immune and other pathways.
Endometriosis Treatment Target Proposed From Genetic Analysis
Researchers used linkage analyses, targeted sequencing, and genotyping to identify endometriosis-associated variants in a potentially targetable receptor coding gene.
Skin Cell Atlas Elucidates Pathological Cell States Underlying Inflammatory Skin Diseases
Researchers profiled the transcriptomes of more than 500,000 single cells from human fetal skin and adult skin with atopic dermatitis and psoriasis.