inflammatory disease Endometriosis Treatment Target Proposed From Genetic Analysis Researchers used linkage analyses, targeted sequencing, and genotyping to identify endometriosis-associated variants in a potentially targetable receptor coding gene. PLOS Papers on Cerebellum Epigenetics, Copy Number Signature Tool, Acute Lung Injury Networks In PLOS this week: epigenetics analysis of brain tissue, bioinformatics tool to find copy number signatures in cancer, and more. Skin Cell Atlas Elucidates Pathological Cell States Underlying Inflammatory Skin Diseases Researchers profiled the transcriptomes of more than 500,000 single cells from human fetal skin and adult skin with atopic dermatitis and psoriasis. Single-Cell Sequencing Reveals Immune Contributors to Exacerbated Asthma in Mouse Model Investigators saw enhanced interleukin-13 production by a handful of immune cell types in mouse models of steroid-resistant asthma. 'Genotype-First' Study Leads to Blood Cell Mutations Underlying Severe Autoinflammatory Disease Premium Since the mutations are only found in a subset of patients' blood cells, the disorder, called VEXAS, might be treatable with a bone marrow transplant. Mar 12, 2020 DIAMONDS Project Using New Classification Approach to Develop Rapid Infectious Disease Tests Premium Feb 3, 2020 IMIDomics, Gossamer Bio Form Immune-Mediated Inflammatory Disease Alliance Jan 20, 2020 Multi-Disease Diagnostic Platform Project Receives €22.5M in EU Funding Apr 11, 2019 Twist Bioscience Providing Antibody Optimization to Pandion Therapeutics for Drug Development Mar 8, 2019 Frontal Fibrosing Alopecia GWAS Implicates Risk Loci with Links to Immune System Jan 30, 2019 iReceptor Plus Consortium Wants to Improve Immunological Data Sharing Premium Jan 15, 2019 Immunological Data Sharing Consortium Wins €8.4M Award From EU, Canada Dec 19, 2018 Inflammatory Bowel Disease, Irritable Bowel Syndrome Show Differences in Gut Microbiomes Jul 28, 2017 Panel Sequencing Leads to Pathogenic Mutations in Autoinflammatory Cases May 31, 2017 IMIDomics, Celgene Partner on Immune-Mediated Inflammatory Disease Research Feb 28, 2017 Centers for Common Disease Genomics Program Standardizes Sequencing Analysis Pipeline Premium Jan 18, 2017 EU Consortium Gets €14M to Personalize Treatment of Inflammatory Diseases Jan 5, 2017 Metabolon, InnVentis Partner to Study Metabolomics in Inflammatory Disease Nov 11, 2015 Team Taps Immune T-Cell Regulators to Find Early Markers of Disease in Blood Apr 24, 2015 Meta-analysis Reveals New Psoriasis Risk Loci in Caucasian, Chinese Populations Feb 2, 2015 Leprosy GWAS Uncovers Risk Variants, Relationship to Inflammatory Disease Jan 29, 2015 Analysis Highlights Strain Diversity in Gut Microbiome Apr 30, 2013 NIAMS to Fund Small Businesses for Inflammatory Disease Biomarker Tools Dec 12, 2012 MDxHealth and Ghent University Begin Collaboration under New Pharmacoepigenomics Center Premium Sep 16, 2011 Cellzome Hits Two Milestones in GSK Kinase Research Pact Premium Load More Breaking News Horse Genetics Study Reveals Origins of Domestication, Use in Human Culture Rady Children's Team Presents Genomic Medicine Management Tool at ASHG Canaccord Genuity Initiates Coverage of Quantum-Si With Buy Rating NIH SenNet Program to Map Rare Senescent Cells Implicated in Human Health Woolly Mammoths Died Out After Climate Shift Eliminated Food Source, Environmental DNA Study Finds Thermo Fisher Scientific Prices $5.85B Senior Notes Offering The Scan Just Breathing A new analysis suggests that most Mycobacterium tuberculosis is spread by aerosols from breathing, rather than by coughing, the New York Times reports. Just Like This One NPR reports that the World Health Organization has hired a South African biotech company to recreate mRNA vaccine for SARS-CoV-2 that is similar to the one developed by Moderna. Slow Start The Wall Street Journal reports that Biogen's Alzheimer's disease treatment had revenues for July through September that totaled $300,000. Genome Research Papers on Cancer Chromatin, Splicing in the Thymus, Circular RNAs in Cancer In Genome Research this week: analysis of bivalent chromatin sites, RBFOX splicing factors' role in thymic epithelial cells, and more.