inflammatory disease

In Genome Biology this week: computational tool to uncover cancer driver mutations, microbial species linked to ankylosing spondylitis, and more.

With new gene sequencing panels, investigators made firm or possible diagnoses in almost one-third of undiagnosed autoinflammation and vasculitis cases.

The deal gives Celgene access to ImiDomics' database of genomic markers derived from biological samples for immune-mediated inflammatory diseases.

The centers are using the standardized pipeline to help streamline data sharing and data analysis to achieve their larger research goals.

The project aims to elucidate markers of response and non-response to current treatment regimens, and to identify new therapies.

The deal joins Metabolon's metabolomics expertise with InnVentis' big data and machine learning platform.

With the help of a newly generated gene regulatory network for T-cell differentiation, researchers identified transcription factors with ties to disease symptoms.

Researchers delved into the roots of psoriasis using genome-wide association study data for almost 35,000 European or Chinese individuals with or without the condition.

Through a multi-stage genome-wide association study, researchers found six new leprosy risk loci, including sites previously linked to inflammatory disease.

A University of Washington-led team looked at strain diversity in human gut microbiomes using a newly developed computational pipeline.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.