After MCW researchers used exome sequencing to provide a diagnosis for a 6-year-old boy with an extreme form of inflammatory bowel disease, the team put in place a broad program to support future clinical sequencing projects. The framework addresses a range of issues that surround diagnostic sequencing — from patient selection to analysis and interpretation, consent and data-sharing policies, and reimbursement.
The company also remains on track with its more advanced familial adenomatous polyposis drug and plans to file within the next two weeks an investigational new drug application to begin testing the therapy in humans.
OSU Medical Center will enroll patients who agree to join Coriell's personalized medicine project under the guidance of their primary care physician. The partners will study the impact of using genomic information in treating chronic conditions.
Lycera, which is developing drugs for autoimmune diseases, will use the cash to advance through Phase II proof-of-concept studies a drug based on University of Michigan research, and into Phase I trials a second candidate based on research conducted at New York University.
MDRNA also reported its fourth-quarter financial results, posting lower operating costs on the elimination of non-RNAi programs and operations the company was working on prior to a corporate reorganization.