inflammation
Aging Clock Developed From Inflammatory Immune Features
With integrated immune profiles for more than 1,000 individuals, investigators established an inflammatory clock of aging that tracks with age-related disease and frailty.
Skin Cell Atlas Elucidates Pathological Cell States Underlying Inflammatory Skin Diseases
Researchers profiled the transcriptomes of more than 500,000 single cells from human fetal skin and adult skin with atopic dermatitis and psoriasis.
Genetic Loci Linked to Risk of Rare Takayasu Arteritis Hint at Related Traits
In a genome-wide association study of Takayasu arteritis, researchers uncovered disease-linked loci both within and beyond the HLA region.
'Genotype-First' Study Leads to Blood Cell Mutations Underlying Severe Autoinflammatory Disease
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Since the mutations are only found in a subset of patients' blood cells, the disorder, called VEXAS, might be treatable with a bone marrow transplant.
Single-Cell Sequencing Reveals How Severe COVID-19 Exacerbated by Type I Interferons
Researchers from South Korea used 10x Genomics' scRNA-seq platform to also find type I IFN-driven inflammatory features in patients with severe influenza.