infertility Male Infertility Exome Sequencing Leads to New Diagnostic, Treatment Insights Investigators identified potential causal variants in 16 genes, including meiotic pathway gene changes that coincided with fertility treatment failure. De Novo Mutations Linked to Male Infertility in Trio Exome Sequencing Study At the ASHG annual meeting this week, a Newcastle University researcher described efforts to find de novo mutations behind oligozoospermia or azoospermia. Yourgene Inks US Distribution Deal for Chemotoxicity Assay, Other Tests The deal includes UK-based Yourgene's test for detecting cancer patients who may have an adverse reaction to 5-fluorouracil, as well as reproductive health tests. Saudi Arabian Study Nearly Doubles Known Genes Associated With Male Infertility The authors from King Faisal Specialist Hospital and Research Center aim to implement exome sequencing as a routine clinical test for male infertility patients. Two Polycystic Ovary Syndrome Subtypes Emerge From Phenotypic Clustering Analysis Premium Phenotypic clustering identified distinct forms of PCOS with specific gene variants, providing a promising strategy for enhancing the treatment of this syndrome. Jun 4, 2020 Igenomix, Ferring Pharmaceuticals Collaborate to Study Infertility, Pregnancy Conditions Jan 31, 2020 Single-Cell Sequencing Study Suggests Antioxidant Pathway Role in Female Fertility Declines Jan 6, 2020 NuProbe Global, CarrierGene Biotech Complete Merger, Partner With Illumina Dec 10, 2019 Celmatix Sues 23andMe for $100M Alleging Breach of Contract Nov 4, 2019 IVF Doesn't Increase Chromosomal Instability in Newborns, Study Finds Jun 19, 2019 Thermo Fisher, Predictive Labs Collaborate on Infertility Genetics Research Feb 5, 2019 Neonatal, Adult Testes Cell Populations Characterized by Single-Cell RNA Sequencing Oct 9, 2018 Celmatix Partners With Onctotest-Teva to Offer Reproductive Health Genetic Test in Israel Aug 30, 2018 Celmatix, Ferring Pharmaceuticals Partner to Study Genomics of IVF Treatment Response Dec 21, 2017 Celmatix Plans to Expand Next Year Following New Funding, Test Approval From NY State Premium Dec 18, 2017 Celmatix Wins $4.5M From New York State to Expand NYC Headquarters Oct 18, 2017 Episona Adds DTC Option for Epigenetic Male Infertility Test, Enters Shifting Regulatory Landscape Premium Feb 22, 2017 23andMe, Celmatix Launch Fertility Research Community Apr 28, 2016 Fraternal Twin Birth Linked to Two Loci in GWAS Mar 4, 2016 Episona Finishing Validation of Epigenetic Male Fertility Test With Eye on Q3 Launch Premium Feb 10, 2016 23andMe Partners With Celmatix to Discover Infertility Biomarkers Dec 9, 2015 Cheetah Genome Harbors Low Levels of Diversity, Gives Glimpse into Evolutionary Past Nov 5, 2015 Exome Sequencing Homes in on Gene Linked to Early Human Embryonic Lethality Oct 19, 2015 Celmatix Launches Personalized Reproductive Medicine Consortium Jul 8, 2015 Sperm RNA-seq Study Reveals Potential Biomarkers for Diagnosing Male Infertility Load More Breaking News European Commission Outlines Intended Restorative Measures for Blocked Illumina-Grail Deal Cross-Trait Meta-Analysis Explores Potential Pleiotropy Across Psychiatric Conditions Bactobio Raises £6M in Private Financing Top Five Articles on GenomeWeb Last Week: Amazon Omics, Ashkenazi Jewish Population History, More AnPac Bio to Raise $5M in Private Placement The Scan Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases. Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes. Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach. Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.