immune system diseases Genetic Study of Skin Pigmentation in African Americans Uncovers Links to Vitamin D Deficiency Starting with a genome-wide association study focused on skin pigmentation, investigators identified genetic variants with additional ties to vitamin D levels. Enpicom Sees Personalized Medicine Coming Into Focus After Busy 2020 Premium The Dutch bioinformatics firm's ImmunoGenomiX technology platform is helping researchers develop therapies for COVID-19 as well as for cancer. HTG to Expand Disease Reach With New Whole-Transcriptome Profiling Product Mid-2021 Premium The firm aims to launch an early-access program by the end of the year, followed by a second white paper before the JP Morgan Healthcare Conference in January. Autoimmunity Insights Gleaned From GWAS of Immune Cell Traits A genome-wide association study focused on hundreds of immune cell features identified genetic risk variants involved in several autoimmune conditions. Adaptive Biotechnologies, Takara Bio T Cell Receptor Sequencing Methods Rank High in Benchmarking Study Premium An international team of researchers put nine immune cell sequencing methods head to head, including RNA-based and DNA-based ones, using the same T-cell sample. Aug 4, 2020 Sequencing Uncovers Mutation, Treatment for Rare Genetic Autoimmune Disorder May 7, 2020 Primary Immunodeficiency Study Highlights Monogenic, Common Variant Disease Contributors Apr 20, 2020 Blueprint Genetics, NICER Consortium Developing Genetic Test for Immunologic, Hematologic Disorders Feb 13, 2020 Blood Vitamin D Levels Tied to Dozens of Genetic Variants in UK Biobank GWAS Jan 20, 2020 Multi-Disease Diagnostic Platform Project Receives €22.5M in EU Funding Dec 19, 2019 Blood Cell Transcriptome Atlas Enables Study of Immune Disorders Jun 13, 2019 GlaxoSmithKline, UC's Doudna Establish $67M Genomics, CRISPR Research Lab May 9, 2019 Enpicom, DDL to Partner on Immunogenomics Sequencing, Analysis Mar 7, 2019 NYCKidSeq Project Aims to Improve Communication of Genomic Test Results Premium Jan 30, 2019 iReceptor Plus Consortium Wants to Improve Immunological Data Sharing Premium Jan 22, 2019 Circulating B Cell Antibody Repertoire in Healthy Individuals is Highly Diverse, Study Reveals Jan 15, 2019 Immunological Data Sharing Consortium Wins €8.4M Award From EU, Canada Nov 15, 2018 Variants Impacting Gene Expression of Immune Cell Types Emerge From Study Nov 13, 2018 1CellBio, Open Medicine Institute Partner on Single-Cell RNA Sequencing Oct 9, 2018 10,000 Immunomes Project Establishes Initial Baseline for Healthy Immune System Sep 28, 2018 Multi-Omic Analysis Finds SCID Gene Therapy Rebuilds Patients' Immune Cells, Microbiomes Aug 2, 2018 Study Lays Path for Development of Epiontis' PCR-Based Cell-Counting Tests Premium Jul 19, 2018 Deep Learning-Based Method Predicts Non-Coding Mutation Effects, Disease Risk Premium Jun 20, 2018 Exome Sequencing Helps Diagnose Primary Antibody Deficiency Patients Apr 26, 2018 Single-Cell Study Finds Chromatin Epigenetic Variability Rises with Age Load More Breaking News UK Biobank Study Investigates Incomplete Penetrance of Mendelian Disease Variants MDxHealth Q3 Revenues Grow 23 Percent BioMérieux Q3 Revenues Increase 11 Percent, Firm Raises 2021 Guidance Germline Cancer Risk Genes May Hold Rhabdomyosarcoma Survival Clues, Study Suggests Danaher Q3 Revenues Rise 23 Percent, Beat Wall Street Estimates Horse Genetics Study Reveals Origins of Domestication, Use in Human Culture The Scan Guidelines for Ancient DNA Work More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature. And Cleared A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times. Suit Over Allegations The Boston Globe reports that David Sabatini, who was placed on leave from MIT after allegations of sexual harassment, is suing his accuser, the Whitehead Institute, and the institute's director. Nature Papers on Esophageal Cancer, Origin of Modern Horses, Exome Sequencing of UK Biobank Participants In Nature this week: genetic and environmental influences of esophageal cancer, domestic horse origin traced to Western Eurasian steppes, and more.