hypertension

Using data from the UK Biobank, researchers explored relative contributions that genetics and lifestyle make to cardiovascular disease and diabetes risk.

The researchers said that examining the FGF21 allele could cast light on potential adverse and beneficial effects of therapies that target the gene.

With the help of electronic health record data, researchers searched for common variants linked to hundreds of diseases or clinical lab measurements.

Through a genome-wide association study and meta-analysis, researchers saw dozens of new and known blood pressure loci, including ancestry-specific associations.

Independent research teams identified mutations in a chloride ion channel gene in some cases of aldosteronism, a condition that can cause severe hypertension.

In a pilot study of 92 individuals with familial or suspected genetic chronic kidney disease, researchers successfully diagnosed 24 percent of cases with exome sequencing.

Gut microbiome researchers have identified features associated with everything from Crohn's disease to salt intake, immune activity, and hypertension.

On a conference call, the firm's CEO said that it and other industry players are pushing to postpone implementation of PAMA to no earlier than July 1, 2018. 

This Week in PLOS

In PLOS this week: blood pressure and hypertension loci in people of African ancestry, Plasmodium vivax population genomics, and more.

Geneticure has raised around $1.1 million to fund the study, which may very well be the largest prospective RCT for personalization of high blood pressure treatment.

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In a statement, National Institutes of Health Director Francis Collins says sexual harassment is "morally indefensible" and "unacceptable."

Octopuses might owe their intelligence to their liberal alterations to their genes, Cosmos reports.

Stat News and ProPublica report that African Americans are underrepresented in cancer clinical trials.

In Cell this week: genomic analysis of abdominal aortic aneurysm, effect of probiotics on the microbiome, and more.