hypertension
The company has been offering the test on a limited basis but now plans to market it more broadly after a large validation study showed high sensitivity and specificity.
Individuals at enhanced polygenic risk of high systolic blood pressure had increased treatment resistance risk and less pronounced response to chlorthalidone in a new study.
PolygenRx Wants to Use Genetics to Guide Chronic Disease Treatments, Starting With Hypertension
Premium
The Australia-based startup wants to partner with drugmakers on biomarker-defined clinical trials and create clinical decision-support software.
Additional Blood Pressure Contributors Uncovered in Large GWAS Meta-Analysis
The loci uncovered in the meta-analysis provided clues to blood pressure biology and enabled the development of new polygenic risk scores.
Scores focused on the biochemical pathways associated with disease and pairing these scores with other risk assessments could improve predictive value, the data showed.