Geneticure has raised around $1.1 million to fund the study, which may very well be the largest prospective RCT for personalization of high blood pressure treatment.
In Nature this week: a CRISPR/Cas9 system that can be toggled, and more.
Tapping data for hundreds of thousands of individuals, three teams uncovered overlaps between blood pressure and other metabolic and immune traits.
The researchers demonstrated that blocking the functioning of certain genes expanded the lifespan of lab animals.
Variants at 12 loci associated with blood pressure traits in European, East Asian, and South Asian individuals overlap with apparent DNA methylation regulators.
A meta-analysis of blood expression data for more than 7,000 individuals highlighted 34 transcripts with blood pressure-associated expression patterns.
The study shines light on the population history of sub-Saharan Africa and provides the basis for future medical genetics studies, including a new pan-African genotype array.
NEW YORK (GenomeWeb) – People armed with genetic information about their risk for developing high blood were more inclined to cut down on their salt intake, researchers from the University of Toronto reported in a study
NEW YORK (GenomeWeb News) — Through both linkage analysis and whole-exome sequencing, an international team of researchers has linked mutations in the protein kinase DYRK1B gene to metabolic syndrome.
Researchers at Utrecht University have completed a proteogenomics study of rat liver tissue, integrating whole genome sequencing, RNA-seq, and mass spec-based proteomics.
The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.
The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.
Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.
In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.