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Aug 10, 2017

Color Moves Beyond Hereditary Cancer Testing With High Cholesterol Genetic Test

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The latest offering puts the genetic testing company on the path toward becoming what it calls a preventive health service company.

Mar 22, 2016

Admera Health Broadens Test Portfolio With Cardiovascular Additions; Plans Liquid Biopsy Assays

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Last week, the firm launched AtheroGxOne the second of two cardiovascular next-gen sequencing panels, and hopes to launch its first liquid biopsy test in 2017.

Nov 12, 2015

Progenika Biopharma Lands CE Mark for NGS Familial Hypercholesterolemia Test

The firm's Seqpro Lipo IS is the first approved NGS diagnostic assay for the disease, which affects one in 300 people.

Mar 11, 2015

Cholesterol Transport Linked to Diabetes Risk

Genetic study of familial hypercholesterolemia implicates link between type 2 diabetes risk and cholesterol transport.

Feb 13, 2015

Alnylam Aims to Release Multi-program Clinical Data in 1H 2015

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The firm also said it aims to soon begin human studies for its hepatic porphyria treatment ALN-AS1 and to select a development candidate for its program in primary hyperoxaluria type 1.

Dec 12, 2014

Alnylam Begins Clinical Trials of ATTR, Hypercholesterolemia Drugs

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Both drugs are administered subcutaneously using Alnylam's GalNAc conjugates.

Nov 13, 2014

Carriers of NPC1L1 Inactivating Mutations Have Lower Coronary Heart Disease Risk, Researchers Say

NEW YORK (GenomeWeb) – Naturally occurring mutations that disrupt NPC1L1 protein function are associated with lower plasma low-density lipoprotein levels and a reduced risk of coronary heart disease, investigators from the Myocardial Infarction Genetics Consortium

Nov 05, 2014

Study IDs New Loci, Explains 5 Percent of Variation in Cholesterol-Lowering Effects of Statins

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Originally published Nov. 4

Oct 30, 2014

Alnylam Files to Begin Phase I Trial of Hypercholesterolemia Drug

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NEW YORK (GenomeWeb) — Alnylam Pharmaceuticals this week announced that it has filed an application with UK regulators to begin a Phase I trial of ALN-PCSsc, a subcutaneously administered siRNA treatment for hypercholesterolemia.

Sep 30, 2014

Researchers Identify Transcriptomic Signature to Predict Statin Response

NEW YORK (GenomeWeb) – Transcriptomic data may help predict how patients respond to treatment with statins, according to a new study from Children's Hospital Oakland Research Institute researchers appearing in Genome Biology

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The Scan

DNA Defense Not Convincing

Two researchers have found that behavioral genetic defenses in criminal cases don't tend to affect outcomes, according to Popular Science.

Keep on Brushing

Researchers report that while host genetics influence the oral microbiome, they don't appear to affect cavity-causing microbes, the Economist says.

Panda Gut Seasonality

Pandas' gut microbiomes change as what they eat changes with the seasons, writes Discover's Inkfish blog.

This Week in PLOS

In PLOS this week: comparative genomic study of malaria-linked macaque parasite, search for apple root reference genes, and more.

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