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hypercholesterolemia

Allelica Wants Polygenic Risk Scores to Become Routine in Heart Disease Care
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The startup has developed software to automate polygenic risk score generation for hospitals and labs using microarray or sequencing data.

Polygenic Variation Affects Disease Risk From Monogenic Variants, Study Finds

Accounting for polygenic background in conditions like hereditary breast cancer or Lynch syndrome can increase the accuracy of disease risk estimation.

Genetic Screening Identifies Many at Risk of Inherited Disease But Missed by Routine Care

Most of the disease risk carriers identified in the Healthy Nevada Project did not meet clinical guidelines for screening, according to the new analysis.

American Heart Association Develops Genetic Testing Guidelines for Cardiovascular Disease

The AHA said genetic testing is useful in the management of several inherited diseases such as cardiomyopathies and familial hypercholesterolemia.

Monogenic Hypercholesterolemia Increases Cardiovascular Disease Risk More Than Polygenic Form

Understanding the genetic causes of hypercholesterolemia could provide prognostic information to help treat patients, the researchers said.

Jan 9, 2020

Mayo Clinic, Helix Partner for 100K-Patient Clinical Genomics Study
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Nov 26, 2019

Geisinger Awarded $2.8M Grant for Familial Hypercholesterolemia Research

Jul 31, 2019

Finnish Exomes Yield New Trait, Disease Associations Involving Rare, Deleterious Variants

Apr 25, 2019

Helix, AdventHealth Partner on Genetic Screening Study

Apr 5, 2019

Healthy Nevada Project Identifies Individuals at Risk for Disease That Are Missed by Guidelines

Sep 11, 2018

Yale to Launch Large-Scale Genomic Medicine Project
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May 16, 2018

FH Foundation, Color Launch Familial Hypercholesterolemia Genetic Testing Study

Nov 13, 2017

Lipid Nanoparticle CRISPR Delivery Can Result in More Efficient Editing Than Viral Delivery

Aug 10, 2017

Color Moves Beyond Hereditary Cancer Testing With High Cholesterol Genetic Test
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Mar 22, 2016

Admera Health Broadens Test Portfolio With Cardiovascular Additions; Plans Liquid Biopsy Assays
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Nov 12, 2015

Progenika Biopharma Lands CE Mark for NGS Familial Hypercholesterolemia Test

Feb 13, 2015

Alnylam Aims to Release Multi-program Clinical Data in 1H 2015
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Dec 12, 2014

Alnylam Begins Clinical Trials of ATTR, Hypercholesterolemia Drugs
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Nov 13, 2014

Carriers of NPC1L1 Inactivating Mutations Have Lower Coronary Heart Disease Risk, Researchers Say

Nov 5, 2014

Study IDs New Loci, Explains 5 Percent of Variation in Cholesterol-Lowering Effects of Statins
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Oct 30, 2014

Alnylam Files to Begin Phase I Trial of Hypercholesterolemia Drug
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Sep 30, 2014

Researchers Identify Transcriptomic Signature to Predict Statin Response

Sep 24, 2014

Sophia Genetics Gets CE-IVD Mark for Genetic Tests

Aug 14, 2014

Alnylam May Seek Approval for TTR Amyloidosis Rx in 2017 as Other Programs Advance
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May 1, 2014

Alnylam Reports Preclinical Data from Hypercholesterolemia, Hypertriglyceridemia Programs
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Breaking News
The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.