hypercholesterolemia Allelica Wants Polygenic Risk Scores to Become Routine in Heart Disease Care Premium The startup has developed software to automate polygenic risk score generation for hospitals and labs using microarray or sequencing data. Polygenic Variation Affects Disease Risk From Monogenic Variants, Study Finds Accounting for polygenic background in conditions like hereditary breast cancer or Lynch syndrome can increase the accuracy of disease risk estimation. Genetic Screening Identifies Many at Risk of Inherited Disease But Missed by Routine Care Most of the disease risk carriers identified in the Healthy Nevada Project did not meet clinical guidelines for screening, according to the new analysis. American Heart Association Develops Genetic Testing Guidelines for Cardiovascular Disease The AHA said genetic testing is useful in the management of several inherited diseases such as cardiomyopathies and familial hypercholesterolemia. Monogenic Hypercholesterolemia Increases Cardiovascular Disease Risk More Than Polygenic Form Understanding the genetic causes of hypercholesterolemia could provide prognostic information to help treat patients, the researchers said. Jan 9, 2020 Mayo Clinic, Helix Partner for 100K-Patient Clinical Genomics Study Premium Nov 26, 2019 Geisinger Awarded $2.8M Grant for Familial Hypercholesterolemia Research Jul 31, 2019 Finnish Exomes Yield New Trait, Disease Associations Involving Rare, Deleterious Variants Apr 25, 2019 Helix, AdventHealth Partner on Genetic Screening Study Apr 5, 2019 Healthy Nevada Project Identifies Individuals at Risk for Disease That Are Missed by Guidelines Sep 11, 2018 Yale to Launch Large-Scale Genomic Medicine Project Premium May 16, 2018 FH Foundation, Color Launch Familial Hypercholesterolemia Genetic Testing Study Nov 13, 2017 Lipid Nanoparticle CRISPR Delivery Can Result in More Efficient Editing Than Viral Delivery Aug 10, 2017 Color Moves Beyond Hereditary Cancer Testing With High Cholesterol Genetic Test Premium Mar 22, 2016 Admera Health Broadens Test Portfolio With Cardiovascular Additions; Plans Liquid Biopsy Assays Premium Nov 12, 2015 Progenika Biopharma Lands CE Mark for NGS Familial Hypercholesterolemia Test Feb 13, 2015 Alnylam Aims to Release Multi-program Clinical Data in 1H 2015 Premium Dec 12, 2014 Alnylam Begins Clinical Trials of ATTR, Hypercholesterolemia Drugs Premium Nov 13, 2014 Carriers of NPC1L1 Inactivating Mutations Have Lower Coronary Heart Disease Risk, Researchers Say Nov 5, 2014 Study IDs New Loci, Explains 5 Percent of Variation in Cholesterol-Lowering Effects of Statins Premium Oct 30, 2014 Alnylam Files to Begin Phase I Trial of Hypercholesterolemia Drug Premium Sep 30, 2014 Researchers Identify Transcriptomic Signature to Predict Statin Response Sep 24, 2014 Sophia Genetics Gets CE-IVD Mark for Genetic Tests Aug 14, 2014 Alnylam May Seek Approval for TTR Amyloidosis Rx in 2017 as Other Programs Advance Premium May 1, 2014 Alnylam Reports Preclinical Data from Hypercholesterolemia, Hypertriglyceridemia Programs Premium Load More Breaking News In Brief This Week: Illumina, Personalis, Proteomedix, and More Ancient DNA Details Population Dynamics Within Andean Tiwanaku Civilization Genomic Data Spanning 2K Years Gives Glimpse of Etruscan Origins, Population Changes People in the News: New Appointments at Hologic, Akoya Biosciences, Caris Life Sciences, More At NSGC, Genetic Counselors Address Race-Based Medicine, Ways to Change New Products Posted to GenomeWeb: Becton Dickinson, Cosmos-ID, OncoDNA, More The Scan US Booster Eligibility Decision The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions. Arizona Bill Before Judge The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction. Additional Genes Wales is rolling out new genetic testing service for cancer patients, according to BBC News. Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.