Huntington's disease

The researchers studied edits generated by more than 40,000 gRNAs and gathered data for more than 109 mutational outcomes to create the software.

Duty to Tell?

A UK woman sues a hospital for not telling her of her father's genetic testing results, the Guardian reports.

This Week in Science

In Science this week: molecular drivers of small cell neuroendocrine carcinomas, and more.

This Week in PLOS

In PLOS this week: Huntington's disease modifiers, possible new Chikungunya virus subgroup, and more.

Six microRNAs appeared to be present at enhanced levels in cerebrospinal fluid from symptom-free individuals with characteristic Huntington disease gene expansions.

Just Don't Tell Me

According to Slate, some people prefer not to know their genetic risk of certain diseases.

This Week in Cell

In Cell this week: regulatory changes in pancreatic cancer, metabolic shifts in Alzheimer's disease, and more.

The researchers observed that eliminating these microsatellite repeat expansion RNAs in patient cells reversed some hallmark features of the diseases.

Researchers used the approach to develop an assay to detect above-threshold triplet repeats in Huntington's disease, but also highlight a variety of other applications.

Researchers have discovered four new proteins that contribute to disease progression in Huntington's Disease. 

Pages

Germany's Project DEAL has come to an agreement with the publisher Wiley over journal access and open-access publishing, ScienceInsider reports.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

A Canadian panel recommends public coverage of the gene therapy Kymriah if its cost comes down, the Globe and Mail reports.

In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.