Huntington's disease | GenomeWeb

Huntington's disease

Researchers have discovered four new proteins that contribute to disease progression in Huntington's Disease. 

Sequence-level analysis of European Huntington's disease haplotype indicates its long history and suggests potential targets for allele-specific gene-targeting therapies.

This Week in Cell

In Cell this week: Lassa virus sequencing study, multi-stage genome-wide association study of Huntington's disease, and more.

A study involving more than 4,000 Huntington's disease cases led to variants on chromosomes 15 and 8 with ties to the age at which symptoms appear.

The partners will develop biomarkers for potential use in drug development targeting the disease. 

The deal does not cover Voyager's fledgling effort to use RNAi to treat amyotrophic lateral sclerosis.

The panel may prove useful in clinical trials of drugs interfering with mutant gene expression, the researchers said.

NEW YORK (GenomeWeb) – PerkinElmer said in its Form 10-Q that it reduced its headcount by 152 employees in the third quarter as a result of a restructuring plan. It also took a pre-tax restructuring charge of $13.2 million in the quarter related to the workforce reduction.

NEW YORK (GenomeWeb News) – Evotec said today that the CHDI Foundation has extended and expanded the two parties' collaboration on Huntington's disease research through 2017.

NEW YORK (GenomeWeb) – The Structural Genomics Consortium and the CHDI Foundation have struck an agreement to discover and characterize new drug targets for Huntington's disease and to make their findings available for use by academic researchers and pharmaceutical and biotechnology companies.


In Nature this week: genetic history of HIV in the US, and more.

There are a few projects aimed at addressing the lack of diversity in genomic research, Technology Review reports.

A national assessment shows that US students lag in the sciences, but suggests that achievement gaps are narrowing.

Harvard's George Church discusses HGP-write with the Journal of the American Medical Association.