Huntington's disease

This Week in Science

In Science this week: molecular drivers of small cell neuroendocrine carcinomas, and more.

This Week in PLOS

In PLOS this week: Huntington's disease modifiers, possible new Chikungunya virus subgroup, and more.

Six microRNAs appeared to be present at enhanced levels in cerebrospinal fluid from symptom-free individuals with characteristic Huntington disease gene expansions.

Just Don't Tell Me

According to Slate, some people prefer not to know their genetic risk of certain diseases.

This Week in Cell

In Cell this week: regulatory changes in pancreatic cancer, metabolic shifts in Alzheimer's disease, and more.

The researchers observed that eliminating these microsatellite repeat expansion RNAs in patient cells reversed some hallmark features of the diseases.

Researchers used the approach to develop an assay to detect above-threshold triplet repeats in Huntington's disease, but also highlight a variety of other applications.

Researchers have discovered four new proteins that contribute to disease progression in Huntington's Disease. 

Sequence-level analysis of European Huntington's disease haplotype indicates its long history and suggests potential targets for allele-specific gene-targeting therapies.

This Week in Cell

In Cell this week: Lassa virus sequencing study, multi-stage genome-wide association study of Huntington's disease, and more.

Pages

NPR reports that with medical data being big business, some companies want to get patients involved.

The Asbury Park Press reports on the startup Genomic Prediction's test to determine an embryo's risk of disease.

In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.

Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.