A genome-wide CRISPR screen has revealed five factors required for HIV infection, but which aren't critical to cell viability, including CD4 and CCR5.
Hologic CEO Steve MacMillan said that the deal is so compelling that the firm needed to do it now.
The firm’s emphasis on automation has yielded Dx products for blood banks, assays for HIV and acute kidney injury, and flexible diagnostic test systems that can adapt to labs’ changing needs.
The firm said that the system is unique because it consists of cell, immunoassay, and nucleic acid tests within one platform.
Sequencing on post-mortem samples from individuals infected with Mycobacterium tuberculosis and HIV revealed diversification and spread of the TB pathogen in the body.
In Nature this week: genetic history of HIV in the US, and more.
The researchers developed a sample prep technique similar to those used to study ancient DNA to amplify and sequence HIV genomes from archival patient samples.
The test enables donor screening laboratories to use PCR-based diagnostic technology to screen donated blood and plasma.
A modified version of a commercially available magnetic bead cell sorting instrument from Miltenyi Biotec could be deployed to areas without cGMP facilities.
Professional, molecular, and tissue diagnostics sales continued to grow during the first three quarters, while diabetes care sales remained in decline.
The New York Times looks at companies using genomic tools to try to quickly identify the cause of patients' infections.
The White House has asked for $2.5 billion in funding to address the COVID-19 outbreak, according to the Associated Press.
A resignation at the Marine Biological Laboratory highlights that institutions are unsure of how to handle researchers previously found to have violated codes of conduct, Nature News says.
In PNAS this week: immune responses that affect heart transplant rejection risk, gene variants associated with thiopurine toxicity, and more.