HIV

In counting defective proviruses, approaches for estimating the size of HIV patients' virus reservoirs are throwing off estimates of treatment effectiveness.

Researchers uncovered differences in diversity and composition in the microbiomes of infants exposed to HIV, as compared to unexposed infants.

The firm is hiring new scientific and managerial staff as it targets distinct markets in Africa for its nucleic acid amplification-based resistance test. 

Prequalification now enables procurement in numerous countries within sub-Saharan Africa that have regulations requiring this type of oversight.

The prototype showed biases at low virus concentrations and the researchers raised concerns over use of whole blood versus plasma HIV RNA as a biomarker. 

The researchers combined epitope tagging and affinity-capture mass spec to investigate interactors of two HIV proteins as they exist in functional viruses.

Researchers in San Diego collaborated with the American Red Cross to enable molecular testing, reducing incidence in the zip codes where screening was offered.

Escape From Editing

Researchers report this week that HIV-1 can become resistant to CRISPR/Cas9 editing.

Two recent studies confirm that CRISPR/Cas9 can edit and inhibit latent HIV provirus, but one of them hints that the virus can develop resistance to excision.

Researchers used viral repertoire sequencing to characterize an early-stage HIV-neutralizing antibody, an important step toward developing a vaccine.

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A University of California, Los Angeles-led team has found turning off the CCR5 gene could improve recovery after a stroke, according to Scientific American.

South Dakota lawmakers are to weigh a bill aimed at teaching the strengths and weaknesses of scientific concepts, the Associated Press and KEVN-Black Hills Fox report.

In Science this week: the synthetic genetic system hachimoji, and more.

Thermo Fisher Scientific says it will no longer sell machines in China's Xinjiang region, according to the Wall Street Journal.