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HIV

The firm will apply its qPCR-enabling technology to detection kits for highly polymorphic regions of HIV that confer resistance to protease inhibitors.

In Cell this week: strategies for targeting leukemia with MLL translocations, new Perturb-seq approach, and more.

Mathais Lichterfeld of the Ragon Institute and Rushdy Ahmad of the Broad Institute will use high-throughput proteomics to find phosphorylation important to HIV replication.

The test, which runs on Hologic's automated Panther system, was granted pre-market approval for HIV-1 viral load monitoring.

A genome-wide CRISPR screen has revealed five factors required for HIV infection, but which aren't critical to cell viability, including CD4 and CCR5.

Hologic CEO Steve MacMillan said that the deal is so compelling that the firm needed to do it now.

The firm’s emphasis on automation has yielded Dx products for blood banks, assays for HIV and acute kidney injury, and flexible diagnostic test systems that can adapt to labs’ changing needs.

The firm said that the system is unique because it consists of cell, immunoassay, and nucleic acid tests within one platform.   

Mycobacterium tuberculosis, scanning electron micrograph

Sequencing on post-mortem samples from individuals infected with Mycobacterium tuberculosis and HIV revealed diversification and spread of the TB pathogen in the body.

In Nature this week: genetic history of HIV in the US, and more.

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The nonprofit Biden Cancer Initiative is suspending its operations, according to the Associated Press.

Researchers examine how white nationalists handle personal genetic ancestry results that conflict with their racist worldview, the New York Times reports.

NPR speaks with research participants before and after they learn their APOE E4 status, which affects their risk of developing Alzheimer's disease.

In PLOS this week: genetic characterization of Toxoplasma gondii strains, Crimean-Congo Hemorrhagic Fever Virus uncovered in Sudan, and more.