The markers could be useful in predicting the incidence of immune reconstitution inflammatory syndrome,an exaggerated inflammatory response that can arise in response to antiretroviral therapy in AIDS patients with cryptococcal meningitis.
A team of researchers from Baylor College of Medicine and University of Texas at Austin have described their strategy for forensically determining the direction of HIV transmission between individuals and identifying index cases.
The Applied Research and Technology Development Award is the single largest amount of non-dilutive funding received by Micronics to date and will help the company add to the menu of tests under development for PanNAT, the company's portable system for nucleic acid amplification-based point-of-care testing.
The companies also said that they have separately resolved a lawsuit filed by Abbott against Qiagen earlier this year related to intellectual property surrounding PCR-based methods for detecting human papillomavirus.
The study, which sequenced and characterized 20 individual genomes, is part of a larger effort at Duke that aims to sequence around 200 genomes and 500 exomes from various disease cohorts including schizophrenia, epilepsy, ALS, and HIV.
At AACC, Rheonix presented three research studies demonstrating its integrated sample prep and PCR testing platform. In addition, the company reiterated its intent to seek regulatory clearance in the US for a warfarin sensitivity genotyping test by the end of the year; followed by a regulatory submission in China for an HPV test.
The study supports the idea of more widespread nucleic acid-based HIV diagnostic testing, which could be a boon for Gen-Probe and Novartis Diagnostics, which offer the only approved NAT for qualitative HIV diagnosis in the US.