The method simplifies previous techniques, and preliminary testing using a microfluidic device indicates it could ultimately be used in low-resource settings.
The scientists fused Cas9 to zinc finger proteins to reduce off-target activity, essentially replacing the other nucleases that had been used with zinc fingers.
Following a beta evaluation of the system, a virology lab in Sheffield, UK, ran a workflow assessment and found improvements with the system.
In PLOS this week: parasitoid wasp sequences in butterflies and moths, nuclear sub-proteome of T. cruzi, and more.
The DxN Veris was recently launched as a CE-marked product with a menu of viral load tests, and will launch in a few years in the US with STD and HAI assays.
Roche's program will now include early infant HIV diagnostics for low- and middle-income countries.
In Science this week: reason for partial HIV vaccine protection, and more.
Investigators at the Walter Reed Army Institute and elsewhere identified human leukocyte antigen variants with ties to enhanced or diminished HIV vaccine protection.
The company aims to launch the qPCR-based test in sub-Saharan Africa.
The tests eligible for the collaboration include a quantitative HIV-1 viral load assay, as well as a qualitative test for active infection and early infant diagnosis.
The Centers for Disease Control and Prevention estimates more people get sick and die from drug-resistant germs than previously thought, the Washington Post reports.
According to the Associated Press, three universities and a healthcare institution are sharing a gift of $1 billion.
New rules seek to limit the type of scientific and medical research that can be used to guide public health regulations, the New York Times reports.
In Nature this week: FreeHi-C approach simulates Hi-C data from interacting genome fragments, and more.