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HIV

This Week in Cell

In Cell this week: strategies for targeting leukemia with MLL translocations, new Perturb-seq approach, and more.

Mathais Lichterfeld of the Ragon Institute and Rushdy Ahmad of the Broad Institute will use high-throughput proteomics to find phosphorylation important to HIV replication.

The test, which runs on Hologic's automated Panther system, was granted pre-market approval for HIV-1 viral load monitoring.

A genome-wide CRISPR screen has revealed five factors required for HIV infection, but which aren't critical to cell viability, including CD4 and CCR5.

Hologic CEO Steve MacMillan said that the deal is so compelling that the firm needed to do it now.

The firm said that the system is unique because it consists of cell, immunoassay, and nucleic acid tests within one platform.   

Mycobacterium tuberculosis, scanning electron micrograph

Sequencing on post-mortem samples from individuals infected with Mycobacterium tuberculosis and HIV revealed diversification and spread of the TB pathogen in the body.

This Week in Nature

In Nature this week: genetic history of HIV in the US, and more.

The researchers developed a sample prep technique similar to those used to study ancient DNA to amplify and sequence HIV genomes from archival patient samples.

The test enables donor screening laboratories to use PCR-based diagnostic technology to screen donated blood and plasma.

Pages

In PNAS this week: carbapenem resistance in Enterobacteriaceae, selection against educational attainment-linked variants, and more.

Technology Review points out that a new US presidential science advisor hasn't been selected.

Researchers find that blood tests might be able to help determine severity of a concussion, Wired reports.

President-elect Donald Trump considers other candidates for director of the National Institutes of Health, Nature News reports.