hereditary cancer Invitae to Provide Genetic Testing Within eMERGE Population Screening Study As a new clinical affiliate, Invitae will test up to 25,000 patients in a study exploring the role of genetics in cancer, heart disease, and other conditions. Intermountain Gets National Stage, Myriad Adds Tumor Profiling Panel With Combined Test Offering Premium Although the logistics still need to be worked out, the partners hope to streamline oncologists' experience ordering tests that can inform patient care. Cancer Heritability Gene Set Expanded With Common Variant Analysis Using a gene-level heritability analysis approach, investigators came up with a collection of genes that come together to influence the risk for more than a dozen cancer types. German Medical Center to Report Polygenic Risk Scores as Part of Clinical Whole-Genome Testing Premium Under the Ge-Med project, University Hospital Tübingen will offer diagnostic whole-genome sequencing for all genetic indications and will include PRS in its reporting. Breast Cancer Risk Gene Associations Refined in Large-Scale Studies Two new studies revealed the prevalence of pathogenic variants in breast cancer-related genes, while highlighting genes that may be most informative in the clinic. Sep 10, 2020 NCCN Updates Guidelines Advising Against Using Polygenic Risk Scores Outside of Clinical Trials Jul 17, 2020 BRCA1/2 Population Screening Predicted to be Cost-Effective in Countries With Different Income Levels Jul 14, 2020 Piper Sandler Initiates Coverage of Progenity With Overweight Rating Jun 18, 2020 After DNA-10K, NorthShore Looks to Expand Genomics Integration Into Primary Care Premium Jun 18, 2020 Promega Maintains Microsatellite Instability IVD Plans Amid Evolving Cancer Test Landscape Premium May 31, 2020 Germline Results From Tumor-Normal Sequencing Guides Precision Therapy in Advanced Cancer Patients May 21, 2020 Q&A: ACMG Work Group Hoping to Spark Discussion on Reporting Germline Findings From Tumor Testing May 19, 2020 UMich Online Tool Aims to Improve Identification of Patients With Hereditary Cancer Risk Premium May 5, 2020 Invitae Study Finds Germline Risk Variants in Wide Range of Prostate Cancer Patients Apr 6, 2020 Myriad Genetics BRCA Test to be Reimbursed in Japan Apr 3, 2020 Adventist Health, CancerIQ Collaboration Identifying More Patients for Guidelines-Supported Genetic Testing Premium Apr 2, 2020 Cancer Researchers Discover Novel Inherited Mutation Predisposing Children to Medulloblastoma Mar 6, 2020 Ambry Genetics +RNA Insight Validation Data Suggests Notable Improvement in Diagnostic Yield Premium Feb 6, 2020 Myriad Genetics Q2 Revenues Decrease 10 Percent; CEO Mark Capone Steps Down Feb 6, 2020 Despite Barriers, Labs Starting to Report Suspected Cancer Risk Mutations Seen in Tumor Testing Jan 23, 2020 Geisinger National Experts Join Genome Medical to Help Implement Population Genomics Programs Premium Dec 6, 2019 Gene Panel Finds Pathogenic Variants Missed by Standard Tests in 5 Percent of Familial Cancer Cases Nov 21, 2019 Myriad Genetics BRACAnalysis Approved by Japanese Regulators Nov 7, 2019 NSGC Panel Divided on Whether Newly Diagnosed Breast Cancer Patients Should Undergo Panel Testing Premium Nov 6, 2019 Invitae Q3 Revenues Grow 51 Percent Load More Breaking News Analysis of Ancient Plaque Points to Agriculture-Related Oral Microbiome Changes in Southern Europe Gene-Disrupting Ultra-Rare Variants More Common in Children With Autism Spectrum Disorder CDC to Withdraw EUA for COVID-19 Test; FDA Revokes Three Other EUAs for Non-Use, Agency Clearance Quidel, Beckman Coulter Settle Legal Dispute Over Cardiac Immunoassay Business Top Five Articles on GenomeWeb Last Week: Pacific Biosciences, Illumina, Natera, and More Canine Genetics Firm Embark Veterinary Raises $75M in Series B Round The Scan Purnell Choppin Dies Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post. Effectiveness May Decline, Data From Israel Suggests The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high. To See Future Risk Slate looks into the use of polygenic risk scores in embryo screening. PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.