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Expressed RNAi drug developer Benitec Biopharma this week provided an update on its pipeline, stating that its two lead programs in cancer-associated neuropathic pain and drug-resistant lung cancer have fallen behind schedule as the company further optimizes its therapeutic candi

Arrowhead Research said this week that it has begun the final processes required to file an investigational new drug application for its RNAi-based hepatitis B treatment ARC-520, including manufacturing, toxicology studies, and preparation of a pre-IND data package for submission

NEW YORK (GenomeWeb News) – A pair of studies in the early, online version of Nature Genetics are highlighting the types of genetic mutations that underlie the liver cancer hepatocellular carcinoma, including forms of the disease related to hepatitis B and hepatitis C virus infection.

Just months after adding a hepatitis B treatment to its pipeline, Arrowhead Research's top official this week said that the company expects the program to yield an investigational new drug application in the first half of next year.

By Doug Macron
Benitec Biopharma last week broke out new details about its in-house pipeline, stating that it aims to have three drugs in clinical studies next year and possibly a fourth by 2014.

Arrowhead Research this week released a white paper detailing the market potential for a hepatitis B therapy and the use of its dynamic polyconjugate siRNA-delivery technology to attack the virus.

Alnylam Pharmaceuticals and Arrowhead Research said this week that they have signed an agreement giving each other access to their respective RNAi drug technologies.

A nucleic acid test marketed by Novartis Diagnostics and manufactured by Gen-Probe to screen individual blood donations for HIV and hepatitis have significantly increased the safety of the South African blood supply, according to recently presented data.

Roche Diagnostics will support a multi-partner project using massively parallel sequencing to develop personalized antiviral treatment strategies for Hepatitis C or B.

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Rady Children's Institute for Genomic Medicine and Deloitte are looking into the use of drones to transport samples for testing. 

Direct-to-consumer genetic testing firm 23andMe is laying off about 100 people.

Researchers from Northwestern University examined dust for antibiotic-resistance genes, New Scientist reports. 

In Science this week: researchers present a computational method for predicting cellular differentiation state from single-cell RNA sequencing data, and more.