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Arrowhead Research's top executive this week broke out details on the company's efforts to move its RNAi-based hepatitis B virus treatment ARC-520 into the clinic, stating that the firm will run two phase I trials in order to speed up the generation of key human data.

Researchers from the Beijing Institute of Biotechnology this week published research suggesting that the suppression of a specific microRNA by the hepatitis B virus is responsible for the cancer growth and metastasis that is sometimes caused by the infection.

NEW YORK (GenomeWeb News) – The UK's Medical Research Council has awarded £10.6 million ($17.1 million) to three new multi-partner projects that plan to develop genome-based personalized medicine approaches to treating rheumatoid arthritis, hepatitis, and Gaucher disease.

Dutch gene therapy firm UniQure threw its hat into the RNAi ring this week, announcing that it has picked up non-exclusive access to Benitec Biopharma's proprietary expressed RNAi technology for use with its nascent Huntington's disease program.

Investigators from Arrowhead Research this week published data on a novel strategy of administering a cholesterol-conjugated siRNA payload independently from its delivery vehicle, showing that the co-delivery method can achieve significant gene target knockdown in non-human prima

The primary motivation for PerkinElmer's acquisition of Chinese infectious disease diagnostic firm Shanghai Haoyuan Biotech, announced this week, is to provide the Waltham, Mass.-based firm entrée into the nucleic acid-based blood screening market, company executives said this we

People in the News: Robert Gish

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Arrowhead Research has appointed Robert Gish as the chairman of its newly created hepatitis B clinical advisory board.

Arrowhead Research last week released new preclinical data on its lead drug candidate, the hepatitis B virus treatment ARC-520, reporting that the agent could trigger up to multi-log reductions in the levels of circulating viral antigens, while lowering levels of the virus' repli

Australian expressed RNAi drug developer Benitec this week provided an update to its pipeline, disclosing that it once again expects to have a candidate in phase I testing next year following its recent acquisition of Tacere Therapeutics.

A Cepheid executive today provided investors with an update on the company's molecular diagnostic pipeline, stating that the firm currently has 14 tests in development for its automated GeneXpert platform and that it expects to offer the broadest test menu of any molecular diagno

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In Nucleic Acids Research this week: mutagenic effects of ultraviolet "A" light, post-transcription effects of synonymous mutations, and more.

Researchers have sequenced the genome of the depth-dwelling giant squid.

Prosecutors have charged a former Drexel University professor with theft for allegedly spending federal grant money on adult entertainment and other unrelated expenses, according to the Philadelphia Inquirer.

 

Chris Collins, a former US representative, has been sentenced to more than two years in prison in an insider trading case involving an Australian biotechnology firm, the New York Times reports.