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hematologic malignancies

Invivoscribe, Complete Genomics Partner to Develop, Commercialize Oncology Biomarker Tests

The companies will collaborate to develop biomarkers tests for minimal residual disease (MRDs) in research and clinical setting using the DNBSeq sequencer.

Clonal Hematopoiesis Longitudinal Study Reveals High-Risk Mutations for Developing Cancer

A study of blood DNA samples from almost 3,400 adults over 60 years of age highlighted how different clonal mutations affect the risk of developing blood cancers.

Model Predicts Blood Cancer Progression Risk for Clonal Hematopoiesis Patients
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A score developed using UK Biobank data can identify patients at high and low risk for blood cancer progression and is starting to be used at Dana-Farber Cancer Institute.

Function Oncology Launches With $28M, Seeks to Transform Precision Cancer Therapy With CRISPR
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The firm unveiled early validation data for its CRISPR-based functional genomics platform, which it hopes to commercialize as another tool doctors can use to individualize cancer care. 

Adaptive Biotechnologies, Takeda Partner to Develop Treatments for Lymphoid Malignancies

The multiyear collaboration will use Adaptive's ClonoSeq assay to measure minimal residual disease status as an endpoint for Takeda’s clinical trials.

Mar 9, 2023

Servier, Qiagen to Develop PCR-Based Companion Diagnostic to Identify IDH1-Mutant Leukemia

Mar 8, 2023

Blood-Based MRD Testing Identifies AML Patients at Risk of Relapse After Stem Cell Transplant

Jan 3, 2023

Israeli Startup JaxBio Snags €8.5M EU Grant to Support Creation of Array-Based Cancer Tests
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Dec 29, 2022

Cellectis Nabs €40M Credit Facility From European Investment Bank to Aid Cell Therapy Development

Dec 28, 2022

Mission Bio, Abiosciences to Develop Analytics For Studying Hematologic Cancers

Nov 16, 2022

Aussie Variant Classification Effort Aims to Reduce Uncertainty in Hereditary Blood Cancer Diagnosis
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Aug 12, 2022

Optical Genome Mapping Gains Momentum for Clinical Applications in Hematologic Disorders
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May 26, 2022

Allogeneic Stem Cell Transplant Outcomes Improve With Diverse Gut Microbes, Immune Cells

Apr 28, 2022

Owkin, ADC Therapeutics Team on AI-Based Biomarker Discovery

Mar 29, 2022

Thermo Fisher Scientific Obtains CE Mark for Ion Torrent Genexus Dx Integrated Sequencer

Mar 9, 2022

Expression, Microbiome Features Provide Pre-Treatment Lung Function Clues for Pediatric Patients

Nov 18, 2021

Precipio Hematologic Malignancy Test Receives NY State Approval

Oct 22, 2021

Genetron Health, Fosun Ink Commercialization Deal for Seq-MRD Test in China

Oct 22, 2020

Genetron Health Licenses ImmuQuad Technology for Blood Cancer Testing

Oct 14, 2020

Germline Variants Contribute to Risk of Developing Aging-Related Clonal Hematopoiesis

Sep 18, 2020

MSK Clonal Hematopoiesis Clinic Aims to Drive New Strategies for Cancer Risk Assessment, Prevention
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Jul 10, 2020

Study Spells Out Immune, Genomic, Epigenomic Interactions in Hematological Malignancies

Jun 22, 2020

BioSkryb, St. Jude Expand Licensing Deal for Dx Applications of Single-Cell Tech

Sep 3, 2019

Molecular Aging Initiative to Profile Clonal Hematopoiesis Consequences in Patient Populations
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May 30, 2019

PreCancer Atlas Attempts to Push Precision Medicine to Early-Stage Disease
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Breaking News
The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.