heart failure Cardior Pharmaceuticals MicroRNA PCR Kit Receives CE Marking The kit measures circulating levels of miR-132 in patients receiving Cardior's experimental inhibitor of that microRNA to help treat heart failure patients. Single-Cell Transcriptomics Study Highlights Heart Failure Features Specific to Genotype Researchers used single-nucleus RNA-seq to see heart failure-related shifts in cell populations and gene expression, including those coinciding with specific pathogenic variants. Global, Local Polynesian Ancestry Influence Disease Risk Among Native Hawaiians Polynesian ancestry — encompassing genetic and lifestyle factors — affects obesity, type 2 diabetes, and heart failure among Native Hawaiians, a new study has found. Hypertrophic Cardiomyopathy Studies Reveal Common Contributors, Risk Score Genome-wide association studies offer a look at the rare and common contributors to the heart condition, pointing to possible prediction and treatment tools. Rare Genetic Variants Can Contribute to Ischemic Heart Failure The findings indicate that rare genetic variants in cardiomyopathy-related genes may also contribute to more common forms of heart failure. May 8, 2020 Dilated Cardiomyopathy Risk Loci, Polygenic Score Emerge From Heart Imaging GWAS Jun 24, 2019 Heart Failure Regulatory Gene Revealed in Tissue Transcriptome Study May 30, 2019 Mouse, Cell Models Shed Light on Variants' Role in Rare Heart Condition Nov 27, 2017 European Consortium Aims to Deliver New Tests, Therapies for Cardiovascular Diseases Premium Oct 12, 2017 Cardiovascular Disease Risk Linked to mtDNA Copy Number Mar 22, 2017 European Project Awarded €10M to Build Biobank, Run GWAS for Sudden Cardiac Arrest Premium Dec 19, 2016 Chemotherapy-Induced Heart Failure Marker Proposed Following GWAS in Breast Cancer Patients Jul 8, 2016 Heart Failure Study at Lund University to Use Arrays, NGS, Mass Spec Premium May 27, 2016 Waters Mass Spec Study Yields Suggestions for Instrumentation Used in Translational Research Premium Dec 1, 2015 Through GWAS, Researchers Link Sleep Gene to Heart Failure Aug 21, 2015 Berg, U of Miami Extend Cardiovascular Disease Collaboration Aug 10, 2015 Study Links Rare Mutations in Cadherin Gene to Mitral Valve Prolapse May 28, 2015 Takeda Partners with Sanford-Burnham on Heart Failure Research Apr 10, 2015 ARCA Stays Committed to Developing Heart Failure Rx with PGx Strategy despite Setbacks Premium Nov 13, 2014 BG Medicine Revenues Down 31 Percent in Q3 Jul 25, 2014 Awaiting IPO, CardioDx Raises $21M in Private Financing May 16, 2014 BG Medicine Posts 17 Percent Drop in Q1 Revenues as Galectin-3 Sales Continue to Decline Premium Mar 20, 2014 New Research Points to miR-25 as a Therapeutic Target for Heart Failure Premium Mar 13, 2014 Genomics in the Journals: 2014.03.13 Nov 22, 2013 Study Suggests BG's Galectin-3 Test Useful in Predicting Hospital Readmissions and Cardiac Events Premium Load More Breaking News Simple HealthKit Raises $8M in Series A Round Top Five Articles on GenomeWeb Last Week: Quantum-Si Layoffs, UBS Coverage Initiations, More LumiraDx Secures FDA Emergency Use Authorization, UK Approval for COVID-19, Flu Test Rarity Bioscience Raises Additional €500,000 Cancer Prognoses Informed by Module-Based Approach, Study Finds The Scan UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers. DNA Biobank Developed for French Kidney Donors, Recipients The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France. Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site. Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.