heart failure Global, Local Polynesian Ancestry Influence Disease Risk Among Native Hawaiians Polynesian ancestry — encompassing genetic and lifestyle factors — affects obesity, type 2 diabetes, and heart failure among Native Hawaiians, a new study has found. Hypertrophic Cardiomyopathy Studies Reveal Common Contributors, Risk Score Genome-wide association studies offer a look at the rare and common contributors to the heart condition, pointing to possible prediction and treatment tools. Rare Genetic Variants Can Contribute to Ischemic Heart Failure The findings indicate that rare genetic variants in cardiomyopathy-related genes may also contribute to more common forms of heart failure. Dilated Cardiomyopathy Risk Loci, Polygenic Score Emerge From Heart Imaging GWAS A GWAS that incorporated magnetic resonance imaging data for UK Biobank participants led to 45 previously undetected risk loci related to dilated cardiomyopathy. Heart Failure Regulatory Gene Revealed in Tissue Transcriptome Study Using samples from heart failure patients and healthy controls, researchers uncovered a gene that, when absent in mice, reduced their risk of heart failure. May 30, 2019 Mouse, Cell Models Shed Light on Variants' Role in Rare Heart Condition Nov 27, 2017 European Consortium Aims to Deliver New Tests, Therapies for Cardiovascular Diseases Premium Oct 12, 2017 Cardiovascular Disease Risk Linked to mtDNA Copy Number Mar 22, 2017 European Project Awarded €10M to Build Biobank, Run GWAS for Sudden Cardiac Arrest Premium Dec 19, 2016 Chemotherapy-Induced Heart Failure Marker Proposed Following GWAS in Breast Cancer Patients Jul 8, 2016 Heart Failure Study at Lund University to Use Arrays, NGS, Mass Spec Premium May 27, 2016 Waters Mass Spec Study Yields Suggestions for Instrumentation Used in Translational Research Premium Dec 1, 2015 Through GWAS, Researchers Link Sleep Gene to Heart Failure Aug 21, 2015 Berg, U of Miami Extend Cardiovascular Disease Collaboration Aug 10, 2015 Study Links Rare Mutations in Cadherin Gene to Mitral Valve Prolapse May 28, 2015 Takeda Partners with Sanford-Burnham on Heart Failure Research Apr 10, 2015 ARCA Stays Committed to Developing Heart Failure Rx with PGx Strategy despite Setbacks Premium Nov 13, 2014 BG Medicine Revenues Down 31 Percent in Q3 Jul 25, 2014 Awaiting IPO, CardioDx Raises $21M in Private Financing May 16, 2014 BG Medicine Posts 17 Percent Drop in Q1 Revenues as Galectin-3 Sales Continue to Decline Premium Mar 20, 2014 New Research Points to miR-25 as a Therapeutic Target for Heart Failure Premium Mar 13, 2014 Genomics in the Journals: 2014.03.13 Nov 22, 2013 Study Suggests BG's Galectin-3 Test Useful in Predicting Hospital Readmissions and Cardiac Events Premium Nov 8, 2013 BG Medicine Q3 Revenues Up 56 Percent, But Potential Nasdaq De-listing Looms Premium Sep 30, 2013 BG Medicine Gets Third Nasdaq Warning in Under a Year, Wins Favorable Preliminary Decision from CMS Load More Breaking News Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Genetic Analysis of H. Pylori Indicates Americas Colonized in One Main Migration Event BillionToOne Raises $55M in Series B Financing GeninCode to Launch Cardiovascular Disease Risk Tests in US With Eversana Top Five Articles on GenomeWeb Last Week: Illumina, Liquid Biopsy, Thermo Fisher Scientific, and More Becton Dickinson Sues Beckman Coulter Over Cell Analysis, Sorting IP The Scan Another Resignation According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug. Novavax Finds Its Vaccine Effective Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19. Can't Be Used The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports. PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.