A Johns Hopkins team reported its finding in JAMA Cardiology, backed by SNP array data from 21,870 participants culled from several large cardiovascular studies.
Exome sequences for thousands of people revealed rare, inherited mutations and de novo mutations in a significant subset of congenital heart disease cases.
The company immediately borrowed $255 million to pay part of the $680 million price tag for Alere's MeterPro cardiovascular and toxicology business and its BNP assay business.
Researchers found variants associated with coronary artery disease and migraine risk at three loci in a genome-wide association study, with opposing directional effects at two index SNPs.
Minneapolis-St. Paul's KARE tells the story of a woman who'd thought she'd dodged genetic hypertrophic cardiomyopathy and sought testing for her children.
Investigators compared RNA sequence data in heart samples from individuals with dilated cardiomyopathy and samples from healthy transplant donor hearts.
The researchers believe that the discovery of the genetic loci linked to T2D and CHD will lead to therapeutic opportunities to lower the risk of both diseases.
Data from several large cohorts suggests that a variant in LILRB5 may produce a propensity for muscle pain or myalgia, upping the risk of statin intolerance.
Variants in CETP-inhibitor and statin target genes helped investigators untangle complex ties between low-density lipoprotein levels and cardiovascular events.
A female mummy showing anatomical signs of atherosclerotic cardiovascular disease was found to carry risky versions of seven heart disease-related SNPs.
Using DNA to sketch crime victims might not be a great idea, the NYTimes says.
Science has its own problem with sexual harassment. What do we do with the research these abusers produce, Wired asks.
Senate Republicans led by Senator Rand Paul (R-KY) are trying to change how the government funds basic research, reports ScienceInsider.
In Science this week: combining genomics and ecology to better understand the effects of natural selection on evolution, and more.