An international team of researchers examined genetic and lifestyle factors linked to heart disease in some 55,600 people.
Using exome sequence and phenotyping data for individuals from longitudinal population studies, investigators began parsing pathogenic mutation effects in the genes.
"The idea is to open up a completely new market for bringing genetics into the lower-risk general population," Invitae CEO Randy Scott told GenomeWeb.
In PLOS this week: role for Notch signaling in congenital heart disease, sciatica risk variants, and more.
An analysis focused on large, rare de novo CNVs has identified copy number changes contributing to conotruncal heart disease in Chinese individuals.
The developer has presented clinical results that provide a base for completing development of a multi-protein test kit and conducting a clinical trial in advance of FDA submission.
Tapping data for hundreds of thousands of individuals, three teams uncovered overlaps between blood pressure and other metabolic and immune traits.
Researchers found distinct genetic differences in the two forms of CHD and discovered three new rare CHD disorders in children.
The European Commission recently awarded the researchers €1.5 million to probe the mechanics of heart failure using proteomic, genomic, and epidemiological approaches.
In a Q&A with Scientific American, a stem cell researcher describes how gene editing could be used to treat or prevent disease.
In PLOS this week: RNA-seq, ChIP-seq to determine metformin response; array-based approach to detect protozoa in blood; and more.
Fast Company takes a look at startups in the nutrigenomic space that aim to offer personalized diet advice.
In a glamorous event, the Breakthrough Foundation gave out more than $25 million in prizes to researchers.
Immunotherapy might treat cancer, but it also appears to come with a risk of a number of side effects, the New York Times reports.