Close Menu

heart disease

A spontaneous coronary condition that is overrepresented in young women had a polygenic risk score linked to lower-than-usual atherosclerosis-related heart disease risk.

Two new papers have identified thousands of genetic loci with ties to more than two-dozen blood cell traits in individuals from up to five ancestry groups.

With a three-pronged approach, a team led by Mount Sinai researchers examined the functional effects of noncoding de novo mutations on cardiac development.

Heart Disease Edits

The New York Times reports on an effort to use gene editing to treat high cholesterol and triglyceride levels in monkeys.

Researchers identified secondary or incidental findings in just over 3 percent of the nearly 22,000 EMERGE III participants, who were profiled with a 109-gene panel.

A GWAS that incorporated magnetic resonance imaging data for UK Biobank participants led to 45 previously undetected risk loci related to dilated cardiomyopathy.

Scoring the Risk

Discover writes that polygenic risk scores could help identify people at risk of disease who might not be spotted using traditional risk factors.

The precision medicine company also is accelerating its push into diabetes, depression, and cardiology after getting its solid-tumor test turnaround down to 9 days. 

Although polygenic risk scores for coronary artery disease can slightly improve standard risk assessment tools, the predicted clinical impact remains small.

With data from UK Biobank participants, investigators identified dozens of snoring-related genetic loci and links to traits such as weight, smoking, and sleep apnea.

Pages

According to CNBC, Pfizer has announced that its SARS-CoV-2 vaccine data won't be ready this week.

A number of United Nations agencies push for scientific findings to be made accessible through open science.

Paris-Saclay University garners international regard following a decade-long effort to establish the new research university, Nature News reports.

In Nucleic Acids Research this week: database to house IndiGen sequencing data, database of SARS-CoV-2 docking scores, and more.