head and neck cancer

A subset of mutation-associated neoantigens appeared to be lost from lung or head and neck tumors that became resistant to anti-PD1 or anti-PD1 and anti-CLTA4 therapy.

Spokespersons from Bio-Rad noted that there appears to be an increasing number of researchers using ddPCR for methylation analyses.

Understanding whether, how, and where HPV integrates into the genome could help predict patient outcomes and make treatment decisions.

The MD Anderson researchers aim to combine computational and functional approaches to investigate genomic alterations as novel therapeutic targets.

Researchers hope to advance the technology to support an assay to help personalize oral cancer treatment by avoiding the development of mucositis.

This Week in Science

In Science this week: how Cas9 works, DNA in biofluids to detect head and neck cancers, and more.

A proof-of-principle study suggests blood and saliva may contain markers for finding and following head and neck squamous cell carcinomas.

This Week in PLOS

In PLOS this week: money metagenomics, DNA methylation patterns in pancreatic cancer, and more.

Kura's clinical collaborators will conduct NGS analysis to identify patients with HRAS mutations and who may also respond to tipifarnib.

The test, called CANScript, combines an ex vivo tumor ecosystem with a machine learning algorithm to predict the therapeutic efficacy of cancer drugs.


Vivek Murthy is no longer the surgeon general of the US, the Associated Press reports.

People around the globe took to the streets to support science — some with signs.

Parents who learn of their increased genetic risk of disease also contend with telling their children about theirs, the New York Times writes.

In PLOS this week: loci linked to body mass index measurements, long non-coding RNA expression and urothelial carcinoma prognosis, and more.