glioma Glioblastoma Transcriptomes Point to Mitochondrial Subtype, Potential Treatment Strategies Using single-cell and bulk RNA sequence data, investigators identified four pathway-based GBM subtypes, including a mitochondrial subtype that appears to respond to related inhibitors. Thermo Fisher Scientific, Agios Pharmaceuticals to Codevelop Glioma Companion Diagnostic Thermo will develop a test using its Oncomine Precision Assay to identify IDH1- and IDH2-positive low-grade glioma patients for treatment with Agios' vorasidenib. Oncologists Make Progress Toward Showing Utility for Brain Cancer Liquid Biopsy Presentations at the American Society of Clinical Oncology's virtual annual meeting included new findings relevant to both blood- and spinal fluid-based approaches. Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions A new paper outlines an upcoming effort to trace tumor development and trajectory in time and space using single-cell genetics and other genomic methods. Glioma Hypermutation May Not Correspond to Checkpoint Immunotherapy Response, Study Suggests A new analysis suggests hypermutation can occur in some chemotherapy-treated gliomas, producing heterogeneous, mutation-rich tumors with poor response to anti-PD-1 treatment. Apr 13, 2020 Pediatric Low-Grade Glioma Molecular and Clinical Analysis Defines Subtypes That Predict Outcome Jan 24, 2019 Memorial Sloan Kettering Using Cerebral Spinal Fluid Liquid Biopsy, Sequencing to Track Glioma Evolution Premium Dec 11, 2018 Brain Tumor Molecular Features Characterized in Individuals With Tumor Predisposition Condition Nov 9, 2018 National Cancer Institute Awards $4M to Brain Tumor Sequencing Projects Oct 15, 2018 Liquid Biopsy Shows Promise for Monitoring Childhood Brain Tumors Aug 7, 2018 Researchers Integrate Genotyping Assay, Drug Delivery Tech for Precision Glioma Treatment Premium Jun 28, 2018 MGMT Promoter Methylation Predicts Survival of Glioma Patients Following Combination Treatment May 14, 2018 Children With Specific Brain Tumors Could Benefit From Added Bevacizumab Sep 28, 2017 Pediatric Glioma Splintered Into Distinct Subgroups by Molecular Meta-Analysis Jun 7, 2017 Fred Hutchinson's Oncoscape Data Visualization Tool Going 3D Premium Apr 10, 2017 Medulloblastoma Marked by Intra-Tumor Mutation Diversity Mar 30, 2017 Two Glioma Subtypes Share the Same Lineage Mar 27, 2017 Brain Cancer GWAS Uncovers 13 New Genetic Markers Associated With Glioma Mar 6, 2017 Glioblastoma Genomic Studies Yield Clues About Evolution, Targeted Treatment Dec 1, 2016 Potentially Prognostic Lower-Grade Glioma Markers Described in Chinese Population Aug 31, 2016 Genetic Analysis Reveals Misidentified Glioma Cell Line Jul 6, 2016 RiboMed Biotechnologies, Tocagen Collaborate on Cancer Prognostics Jun 30, 2016 Annai Preps NGS Data Management Platform for Formal Launch; Unveils Early Customer Premium Jun 28, 2016 Glioma Consortium Taps Annai's NGS Data Management Solution for Tumor Research Apr 20, 2016 Oligodendroglioma Subgroups Identified Using Multiple Omics Profiling Load More Breaking News BTIG Initiates Coverage of Berkeley Lights With Buy Rating Quest Diagnostics to Offer Biocept's Target Selector NGS Lung Cancer Test Novacyt 2020 Revenues Surge on Strong Demand for SARS-CoV-2 Testing Products Leidos Wins CDC Bioinformatics Contract Worth up to $13M Thermo Fisher Scientific Next-Generation SARS-CoV-2 PCR Test Nabs CE-IVD Mark Cytosine Base Editor Enables Genome-Wide Genetic Function Screening The Scan Renewed Gain-of-Function Worries The New York Times writes that the pandemic is renewing concerns about gain-of-function research. Who's Getting the Patents? A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports. Other Uses CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2. PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.