glioblastoma

While using stem cells allows Stemina to "make the tissue type of interest. It's an all-human system," and allows the firm to build "the best potential in vitro environment to study a particular question," its CEO said.

Pfizer and Qiagen have expanded their personalized medicine portfolio with an Rx/Dx collaboration in glioblastoma multiforme.

Qiagen's DxS subsidiary will develop a PCR-based test to help identify ideal patients for a vaccine that Pfizer is developing for glioblastoma multiforme.

The scientists said the project illustrates that thorough sequence analyses of cancer genomes can be done quickly, efficiently, and at a low cost outside of the large sequencing centers.

Researchers from the University of California at Los Angeles have sequenced and started characterizing the genome of a widely used glioblastoma multiforme brain cancer cell line called U87MG.

Using gene expression profiling and other genomic approaches, members of the Cancer Genome Atlas Research Network have identified and characterized four glioblastoma multiforme subtypes.

The findings help validate Therasis' bioinformatics and systems biology approach to reconstructing maps of regulatory networks in specific cancer cell types.

In an interview with Pharmacogenomics Reporter this week, Hakan Sakul provided a snapshot of Pfizer's efforts in personalized medicine, the company's stance on regulatory issues, and its overall focus on "omics"-guided medicine.

NCI Director John Niederhuber said last week that the institute plans to expand the Cancer Genome Atlas project to 20 to 25 major tumor types, and to apply next-generation sequencing to at least 100 tumor samples for each of several types of childhood cancers under the TARGET initiative.

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Johns Hopkins University's Genetics and Public Policy Center, National Cancer Institute, Santoris, RayBiotech

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An analysis of UK Biobank data finds hemochromatosis to be more prevalent than thought, according to the BBC.

An analysis finds that female biomedical researchers receive fewer prizes than male ones, and when they do win prizes, they are less prestigious.

In Nature this week: improved genomic analysis using a graph genome reference, tumor mutational burden could predict clinical response to immune checkpoint inhibitors, and more.

Federal researchers tell the Los Angeles Times that the shutdown is causing missed research opportunities as they try to keep their experiments going.