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glioblastoma

The goal is to identify patient-specific rearrangements in the primary tumor, and then check for the presence of that rearrangement in the patient's blood during treatment in order to determine tumor progression and monitor therapy response.

A donation will fund the Yale Program in Brain Tumor Research, an effort to sequence and analyze tumors for important mutations.

Using microarray analyses, researchers have detected a stem cell-related gene expression pattern in an aggressive subtype of glioblastoma multiforme that involves cells expressing the transmembrane protein CD133.

Four projects have received funding from the NIH, including a proteomics-directed study targeting Mycobacterium tuberculosis and an NCI multi-site prospective study of glioma patients.

In particular, George Mason University researcher Emanuel Petricoin expressed concerns about the project's plan to use samples from different patient cohorts for its discovery and verification stages.

The combined grants are worth nearly $650,000 and are meant to support work on treatments for cancer and Huntington's disease.

The slew of PGx abstracts presented by the drug giant at the annual oncology meeting highlighted its “focused approach to cancer drug development through the identification and validation of molecular targets,” Pfizer said.

While using stem cells allows Stemina to "make the tissue type of interest. It's an all-human system," and allows the firm to build "the best potential in vitro environment to study a particular question," its CEO said.

Pfizer and Qiagen have expanded their personalized medicine portfolio with an Rx/Dx collaboration in glioblastoma multiforme.

Qiagen's DxS subsidiary will develop a PCR-based test to help identify ideal patients for a vaccine that Pfizer is developing for glioblastoma multiforme.

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Mainichi reports that 43 percent of Japanese individuals said they did not want to eat agricultural products that had been modified using gene-editing tools.

Two US Department of Agriculture research departments are moving to the Kansas City area, according to the Washington Post.

Slate's Jane Hu compares some at-home genetic tests to astrology.

In PLOS this week: analysis of polygenic risk scores for skin cancer, chronic pain GWAS, and more.