By profiling the mutation patterns in secondary GBM cases, researchers found recurrent MET alterations and attempted to target it with a MET kinase inhibitor.
Using archived tumor samples from individuals with glioblastoma, researchers saw methylation variability at progression, along with potential prognostic hints.
Researchers uncovered subclones within pediatric glioblastoma and diffuse intrinsic pontine glioma patients that influence the abilities of neighboring cells.
With sequence data for more than 118,000 tumors profiled at Foundation Medicine, investigators tracked PDL1 amplification prevalence and possible treatment implications.
The Ivy Glioblastoma Atlas includes newly generated anatomical and transcriptional profiles for dozens of tumors, combined with genomic data from TCGA.
Isoma, which launched last year, will use the funds to develop and clinically validate a molecular test for stratifying glioblastoma patients.
New York Genome Center, Rockefeller University, and IBM researchers combined whole-genome sequencing with Watson to analyze a glioblastoma sample.
Amoy will supply its CD95 IHC and CpG2 qPCR kits to develop a companion diagnostic for Canbridge's lead product targeting recurrent glioblastoma multiforme.
For the first time, the researchers also found a clear difference in risk factors for high-grade glioblastoma versus low-grade glioma.
Mutation and expression patterns in longitudinal, multifocal, and solitary tumor samples suggest glioblastoma follows a multiverse model of evolution.
The Guardian reports that the Mammalian Genetics Unit at the Harwell Institute is to close.
Scientific research itself contributes to plastic waste and isn't very sustainable, FiveThirtyEight reports.
Restaurants in the US may soon serve AquaBounty's genetically modified salmon, according to the Associated Press.
In Science this week: three studies from the Ruminant Genome Project, and more.