For the first time, the researchers also found a clear difference in risk factors for high-grade glioblastoma versus low-grade glioma.
Mutation and expression patterns in longitudinal, multifocal, and solitary tumor samples suggest glioblastoma follows a multiverse model of evolution.
Tempus will provide sequencing and analysis for glioblastoma patients in a clinical trial at Duke using engineered poliovirus as a treatment.
Investigators explored computational strategies for identifying microRNAs that are most relevant to tumor development and progression.
In PNAS this week: link between gene flow restriction and insecticide resistance in malaria mosquitos, cotton leaf shape genetics, and more.
The research team established that its model can be used to determine the optimal dose of radiation therapy for individual patients.
Dartmouth researchers characterized 5-methylcytosine and 5-hydroxymethylcytosine marks in more than two dozen glioblastoma samples.
Short tandem repeat and expression data indicate that the U87MG cell line in the ATCC collection no longer represents the glioma from which it was established.
The companies will collaborate on clinical trials that utilize Tocagen's investigational treatment and RiboMed's prognostic assay technology.
A team of German researchers identified the four-microRNA signature and said it might inform treatment decisions.
The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.
The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.
Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.
In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.