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Investigators teased out imaging signals and underlying biology that can differentiate the subset of brain cancers for which tumor DNA can be detected in blood.
The company has been collecting data on broader applicability of its electric field chip technology for potential use in DNA, RNA, exosome, and protein applications.
In PNAS this week: remethylation of DNMT3A in mice affects expansion of myeloid cells, glycan and receptor expression in glioblastoma, and more.
Functional enhancers can accompany oncogenes on the circularized extrachromosomal amplicons found in glioma and other tumors, enhancing cancer growth.
Although the study was small, the investigators believe it provides proof of principle for the usefulness of cell-free DNA to prognose and monitor glioblastomas.
In PNAS this week: transcriptomic and epigenomic sequence differences in glioblastoma models, approach to analyze small amounts of extracellular RNA, and more.
UK researchers have detected RNA biomarkers in extracellular vesicles that are potentially correlated to aggressive mesenchymal glioblastoma cells.
In Cell this week: malignant cellular states in glioblastoma, method for predicting long-term outcomes among cancer patients, and more.
In Genome Research this week: genomic architecture of glioblastoma, predictive computational approach to estimate SNP fitness, and more.
Kiyatec's cell-based assays model and predict patient therapeutic response to drive cancer drug development and potentially guide treatment.
New analyses indicate female researchers are publishing less during the coronavirus pandemic than male researchers, according to Nature News.
A study suggests people with the ApoE e4 genotype may be more likely to have severe COVID-19 than those with other genotypes, the Guardian says.
Direct-to-consumer genetic testing companies are searching for a genetic reason for why some people, but not others, become gravely ill with COVID-19, the Detroit Free Press reports.
In PNAS this week: forward genetics-base analysis of retinal development, interactions of T cell receptors with neoantigens in colorectal cancer, and more.