glioblastoma
Brain Cancer Study Reveals Immune Cell Populations Linked to Aggressive Subtype
Researchers used single-cell RNA sequencing and spatial transcriptomics to find two myeloid-derived suppressor cell subsets supporting the growth of an aggressive glioblastoma.
Researchers narrowed in on dual-treatment targets using expression and regulatory programs found in glioblastoma cells in and around the tumor.
Cure51 Partners With Cambridge University Hospitals, Others to Expand Cancer Survival Study to UK
Eight NHS cancer centers will examine tumors from patients with exceptional survival times, focusing on three aggressive cancer types.
Glioma Organization Untangled Using Spatial Transcriptomic, Proteomic Profiles
Researchers saw disorganized and structured regions that appeared to reflect hypoxia conditions in glioma, along with five cell state layers within the structured parts of a tumor.
Microenvironments Give Clues to Distinct Immunotherapy Responses in Brain Metastases, Glioblastomas
Investigators found microenvironment differences in checkpoint blockade immunotherapy-treated cases involving brain metastases versus recurrent glioblastoma.