glioblastoma
Wellcome Leap Launches $55M Program to Develop Disease-Specific Tissue Profiling Platforms
The US nonprofit founded by the UK's Wellcome Trust will fund collaborative research projects to build multiscale and multimodal "tissue time machines."
Glioblastoma Omics Study Highlights Informative Tumor Features, Immune Subtypes
Genomic, transcriptomic, proteomic, and post-transcriptional modification features in nearly 100 GBM tumors offered clues to tumor biology, revealing four immune subtypes.
Glioblastoma Transcriptomes Point to Mitochondrial Subtype, Potential Treatment Strategies
Using single-cell and bulk RNA sequence data, investigators identified four pathway-based GBM subtypes, including a mitochondrial subtype that appears to respond to related inhibitors.
NCI researchers performed a multi-platform study to elucidate the factors that can contribute to a patient's better-than-expected response to a drug.
Glioblastoma Brain Tumor Treatment Strategies Stem From Pharmacogenomic Analysis
By screening more than 1,500 drugs against patient-derived glioblastoma cells, researchers tracked down tumor alterations with apparent ties to proteasome inhibitor response.