glioblastoma Wellcome Leap Launches $55M Program to Develop Disease-Specific Tissue Profiling Platforms The US nonprofit founded by the UK's Wellcome Trust will fund collaborative research projects to build multiscale and multimodal "tissue time machines." Glioblastoma Omics Study Highlights Informative Tumor Features, Immune Subtypes Genomic, transcriptomic, proteomic, and post-transcriptional modification features in nearly 100 GBM tumors offered clues to tumor biology, revealing four immune subtypes. Glioblastoma Transcriptomes Point to Mitochondrial Subtype, Potential Treatment Strategies Using single-cell and bulk RNA sequence data, investigators identified four pathway-based GBM subtypes, including a mitochondrial subtype that appears to respond to related inhibitors. Exceptional Responders Cancer Study Points to Possible Treatment Targets Premium NCI researchers performed a multi-platform study to elucidate the factors that can contribute to a patient's better-than-expected response to a drug. Glioblastoma Brain Tumor Treatment Strategies Stem From Pharmacogenomic Analysis By screening more than 1,500 drugs against patient-derived glioblastoma cells, researchers tracked down tumor alterations with apparent ties to proteasome inhibitor response. Jul 8, 2020 Glioblastoma, Developing Brain Cell Populations Show Similarities in Single-Cell RNA-Seq Study Jun 9, 2020 Glioblastoma Genomes Point to Non-Coding Driver Mutations Jun 5, 2020 University of Utah Spinout Eigengene Developing Genome-Wide Signatures for Cancer Diagnostics Premium May 31, 2020 Oncologists Make Progress Toward Showing Utility for Brain Cancer Liquid Biopsy Mar 19, 2020 Imaging Could Help ID Brain Cancer Patients Eligible for Plasma Testing Premium Feb 11, 2020 Biological Dynamics Aims to Boost Adoption of Raw Sample Biomarker Tech Through Microsoft Program Premium Nov 21, 2019 Extrachromosomal Oncogene Amplification Involves Rearrangement of Regulatory Elements Oct 30, 2019 Liquid Biopsy Shows Promise in New Brain Cancer Study Aug 26, 2019 Extracellular Vesicles Provide Biomarkers for Glioblastoma Tumor Subtyping Premium May 7, 2019 Kiyatec Targeting Clinical Oncology Space With 3D Cell Culture Technology Premium Mar 21, 2019 Glioblastoma Driver Mutations Appear Long Before Diagnosis, Evolutionary Analysis Suggests Feb 22, 2019 Expression-Based Survival Signature Proposed for Glioblastoma Feb 11, 2019 Glioblastoma Markers of Checkpoint Immunotherapy Response Discovered Jan 3, 2019 Glioblastoma Pathway Signatures, Treatment Responses Differ Between Male, Female Patients Nov 9, 2018 National Cancer Institute Awards $4M to Brain Tumor Sequencing Projects Oct 18, 2018 Secondary Glioblastoma Genomics Study Leads to Proposed Treatment Target Aug 28, 2018 Epigenetics of Glioblastoma Progression Characterized with Integrated Data Jul 2, 2018 Cooperation Among Pediatric Brain Cancer Tumor Cell Subpopulations Boosts Tumorigenic Ability Jun 15, 2018 PDL1 Amplifications Mark Subset of Solid Tumors, May Point to Checkpoint Blockade Response May 10, 2018 Glioblastoma Atlas Offers Transcriptional Insights Linked to Anatomical Features Load More Breaking News Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets LSU Health Sciences Center Wins $2.4M to Lead SARS-CoV-2 Variant Sequencing Program NanoString Technologies, Parker Institute for Cancer Immunotherapy Partner on Cell Therapy Project BGI Americas Collaborating With Champions Oncology on Proteomic Cancer Research Personal Genome Diagnostics Inks Cancer Genomic Profiling Deal with Duke University Health System The Scan Missed Early Cases A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports. Limited Journal Editor Diversity A survey finds low diversity among scientific and medical journal editors, according to The Scientist. How Much of a Threat? Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned. PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.