glioblastoma
Wellcome Leap Launches $55M Program to Develop Disease-Specific Tissue Profiling Platforms
The US nonprofit founded by the UK's Wellcome Trust will fund collaborative research projects to build multiscale and multimodal "tissue time machines."
Early Trial Responses
A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.
Glioblastoma Omics Study Highlights Informative Tumor Features, Immune Subtypes
Genomic, transcriptomic, proteomic, and post-transcriptional modification features in nearly 100 GBM tumors offered clues to tumor biology, revealing four immune subtypes.
Genome Biology Papers on My Personal Mutanome, GBM Splicing, Gastric Cancer Transcripts
In Genome Biology this week: a database of clinically actionable alterations, alternative splicing patterns in glioblastoma, and more.
Glioblastoma Transcriptomes Point to Mitochondrial Subtype, Potential Treatment Strategies
Using single-cell and bulk RNA sequence data, investigators identified four pathway-based GBM subtypes, including a mitochondrial subtype that appears to respond to related inhibitors.