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The researchers used a method known as paired-end tag sequencing, or DNA-PET, to identify five recurrent gene fusions in Asian populations with gastric cancer.
New loss-of-function mutations in a gene called ATM were implicated in gastric cancer risk, based on genotyping profiles for thousands of gastric cancer cases and controls in Iceland.
The research may lay the groundwork for a noninvasive test for GI or other types of cancer without prior knowledge of which organ is affected.
The research also uncovered other mutations that might be associated with these cancers in patients who do not have a CDH1 mutation.
The agreement expands the partners' alliance to include additional diseases within the gastrointestinal tract.
The non-invasive, blood-based circulating tumor cell and circulating tumor DNA cancer tests will be made available to 19 million patients.
In GIST tumors lacking genetic mutations, researchers uncover an epimutation affecting a gene promoter.
NEW YORK (GenomeWeb) – The non-profit No Stomach for Cancer said today it has awarded $100,000 to fund two research projects that will investigate the genetic basis of gastric cancer.
NEW YORK (GenomeWeb) – Two research teams reported on mutational patterns present in gastric cancer in Nature Genetics.
NEW YORK (GenomeWeb News) – Response Genetics today said it has signed agreements with four payors to provide access to the molecular diagnostic firm's tests.
The Washington Post reports that the CDC's SARS-CoV-2 test issues reflect earlier ones it had with Zika virus testing.
NPR writes that even with thousands of new COVID-19 papers, each should be evaluated based on its own quality.
Researchers traced a gene cluster linked to COVID-19 severity to Neanderthals, the New York Times reports.
In PNAS this week: soil bacteria-derived small molecules affect centrosomal protein, microfluidics approach for capturing circulating tumor cells, and more.