gastric cancer

Patients with PD-L1-expressing gastric or gastroesophageal junction tumors can now be identified for potential treatment with Keytruda using Agilent's assay.

Researchers developed a gene expression-based classifier for four gastric cancer subtypes and found that some are associated with better outcomes than others.

Shared gastric adenocarcinoma tumor features seem to span geography and ethnicity, despite shifts in the proportion of tumors from different molecular subtypes.

Eleven new recommendations were issued to address appropriate HER2 testing and clinical guidance in individuals with advanced gastroesophageal adenocarcinoma.

The company's technology will be used to analyze samples from a large cohort of Chinese volunteers to identify biomarkers for early cancer detection.

This Week in PNAS

In PNAS this week: gene mutations linked to gastric cancer development, genetic determinants that influence reward processing, and more.

The three organizations are inviting comment from health professionals on the recommendations.

Along with breast, ovarian, and pancreatic cancers, the "signature 3" mutation pattern was detected in around 10 percent of sequenced gastric tumors.

This Week in PNAS

In PNAS this week: regenerative flatworm genome, transmission patterns of autism-linked de novo mutations, and more.

The researchers used a method known as paired-end tag sequencing, or DNA-PET, to identify five recurrent gene fusions in Asian populations with gastric cancer.

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A research duo estimates in PLOS One the number of papers that have used misidentified cell lines.

UK's National Institute for Health and Care Excellence approves GlaxoSmithKline's SCID gene therapy despite cost.

Science reports that Brazilian researchers are petitioning for the reversal of budget cuts.

In PLOS this week: gene flow patterns in common ash, guidelines for using morpholinos in zebrafish, and more.