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Avapritinib is sold by Blueprint Medicines as Ayvakit for the treatment of adults with unresectable or metastatic GIST harboring a PDGFRA exon 18 mutation.
In PLOS this week: computational tool to uncover selection within populations, sequencing-based analysis of canine lymphoma, and more.
The team will launch a Phase II study to validate early-stage gastric cancer micro-RNA biomarkers and eventually develop liquid biopsy tests.
The company recently presented results from its Aurora assay for multi-cancer screening and plans to launch a $100 test for the US and Chinese markets.
In PNAS this week: study of central nervous system inflammation roots, circulating immune cells in cancer reflect patient response to treatment, and more.
Investigators are building upon an initial case study that allowed them to assess how well ctDNA captured a cancer's full genomic heterogeneity compared to tissue biopsies.
In Science this week: mass spectrometric analysis of the SARS-CoV-2 spike protein, and more.
Alcohol use in combination with ALDH2 mutations or germline changes in the CDH1 gene corresponded to a subset of diffuse-type gastric cancer cases in East Asian individuals.
The companies are looking to model gene expression signatures to predict treatments for gastric cancer and improve patient stratification methodologies.
Palmetto has expanded the local coverage determination for the Guardant360 liquid biopsy assay to be used with the majority of advanced solid tumors.
Howard Hughes Medical Institute will be requiring its researchers to publish their work so it is immediately accessible to the public, ScienceInsider writes.
The Huffington Post reports that Francis Collins, the director of the US National Institutes of Health, has urged Americans to recommit to reason.
About 150 million rapid coronavirus tests purchased by the US federal government are to be distributed to nursing homes, colleges, and the states, according to the New York Times.
In Nature this week: multi-omic analysis of Alzheimer's disease brain samples, de novo assembly of a diploid potato, and more.