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In Genome Biology this week: a database of clinically actionable alterations, alternative splicing patterns in glioblastoma, and more.
In Nature this week: reference genomes for the platypus and echidna, single-cell RNA sequencing analysis of gastric adenocarcinoma, and more.
Researchers used single-cell RNA sequencing to delve into intra-tumoral heterogeneity in peritoneal carcinomatosis, identifying a potential prognostic signature.
In PNAS this week: Andean and Amazonian population genetics, lipid metabolism changes in gastric cancer linked to ferroptosis avoidance, and more.
The Chinese company is branching out from its core genomics business to liquid biopsy cancer screening and monitoring as it eyes areas for global expansion.
The Chinese company reported revenues of RMB112.0 million ($16.5 million), driven by growth in sales of both its LDT services and IVD products.
The assay underwent clinical validation at three centers in Singapore and 5,248 patients were ultimately screened using the test.
Besides speeding up and increasing enrollment, the Guardant360 test identified a greater number of actionable mutations than tissue-based genotyping.
Avapritinib is sold by Blueprint Medicines as Ayvakit for the treatment of adults with unresectable or metastatic GIST harboring a PDGFRA exon 18 mutation.
In PLOS this week: computational tool to uncover selection within populations, sequencing-based analysis of canine lymphoma, and more.
SARS-CoV-2 vaccine developers are evaluating further vaccine doses as well as modified doses to keep up with new viral variants, according to CNN.
The New York Times reports that a new viral variant of concern has been identified in New York City.
In Nature this week: spatiotemporally resolved map of the human cell cycle, folding single-cell RNA sequencing into cancer drug studies, and more.
According to BBC News, the global vaccine-sharing initiative has sent its first shipment, which arrived in Ghana this week.