fragile X syndrome Small Portion of Individuals With Autism Undergo Recommended Clinical Genetic Testing Individuals with autism spectrum disorder who were younger or with a more severe condition were more likely to undergo genetic testing, a new analysis has found. DNA Methylation Mapping in Genetic Syndromes Leads to Disease-Specific Episignatures Researchers identified 34 episignatures that could be used for diagnostic testing and the interpretation of ambiguous genetic test results. Asuragen Fragile X Diagnostic Test Gets FDA Authorization The firm's AmplideX Fragile X Dx and Carrier Screen Kit is intended to help diagnose fragile X syndrome and assess parental risk of having a child with the syndrome. First Epigenetic Signature Test for Inherited Disorders to Launch in the US, Europe Premium The clinical genome-wide DNA methylation test can diagnose genetic diseases that are missed by exome or genome sequencing and evaluate variants of unknown significance. Systematic CRISPR-Cas9 Analysis Leads to Development of Gene Editing Prediction Tool The researchers studied edits generated by more than 40,000 gRNAs and gathered data for more than 109 mutational outcomes to create the software. Oct 22, 2018 Asuragen, RTI Collaborate on Fragile X Syndrome Testing Feb 15, 2018 DNA Methylation Editing Rescues Neurons in Fragile X Syndrome Nov 21, 2017 Illumina-Developed Software Helps Find Repeat Expansions to Aid Disease Detection Premium Oct 27, 2017 Australian Study Highlights Carrier Screening Impacts in Reproductive Context Jul 20, 2017 Rice U Team Debuts Modular Probe Method to Detect Hypervariable, Long, or Repetitive DNA Sequences Premium Feb 21, 2017 Asuragen to Develop IVD Kits on Thermo Fisher Scientific's CE Platform Feb 2, 2017 North Carolina Looks to Expand Newborn Screening for Severe Genetic Conditions Premium Dec 12, 2016 Asuragen Research Correlates FMR1 Methylation, Symptoms in Fragile X-Associated Motor Disorder Premium Sep 9, 2016 Ontario Hospital Moves Toward Clinical Use of Methylation Array Fragile X Screening Test Premium Aug 12, 2016 New Fragile X Assays From NIH Could Reduce Testing Cost, Improve Sensitivity Premium Apr 19, 2016 Fragile X Testing May Benefit From Direct Sequencing, Methylation Analysis Premium Sep 24, 2014 Emory Wins $8M Grant for Sequencing Study of FMR1 Gene, Fragile X Variations Sep 17, 2014 Asuragen PCR Assay Provides More Evidence of Risk Factors for Mutation Expansion in Fragile X Premium Jul 10, 2014 New York State Issues Permit to Asuragen to Offer Fragile X, Thyroid Cancer MDx May 29, 2014 Dx Focus: Meridian Illumigene Assays; Biofactory FMR1 Identification Kit Premium Mar 21, 2013 Asuragen Presents Data Backing New Molecular Test as Better Predictor of Fragile X Risk in Offspring Premium Oct 23, 2012 Team Explores PacBio for Fragile X Sequencing; Sees Potential for Diagnostics, Newborn Screening Premium Jan 19, 2012 Finnish Team Develops Multiple Heat Pulse PCR Method for Amplification of GC-Rich Regions Premium Oct 6, 2011 Asuragen Using NICHHD Grant to Adapt Fragile X MDx Assay for Newborn Screening Premium Jun 30, 2011 Asuragen, MIND Institute Show Potential of Methylation PCR for Fragile X Testing Premium Load More Breaking News FDA Revises SARS-CoV-2 Test Emergency Use Authorization Requirements to Account for Variants Geisinger Wins $5M NIH Grant to Develop Point-of-Care Genetic Diagnostic Tool Second Genome, Virginia Commonwealth University Partner on NASH Biomarker Discovery LGC Receives CE Mark for AccuPlex SARS-CoV-2, Flu A/B, RSV Reference Material Kit Esophageal Cancer Testing Firm Lucid Diagnostics Files For IPO Twist Bioscience, DeepCDR Collaborate on Antibody Library Design The Scan Booster for At-Risk The New York Times reports that the US Food and Drug Administration has authorized a third dose of the Pfizer-BioNTech SARS-CoV-2 vaccine for people over 65 or at increased risk. Preprints OK to Mention Again Nature News reports the Australian Research Council has changed its new policy and now allows preprints to be cited in grant applications. Hundreds of Millions More to Share The US plans to purchase and donate 500 million additional SARS-CoV-2 vaccine doses, according to the Washington Post. Nature Papers Examine Molecular Program Differences Influencing Neural Cells, Population History of Polynesia In Nature this week: changes in molecular program during embryonic development leads to different neural cell types, and more.