familial adenomatous polyposis
Cancer Moonshot-funded teams are profiling pre-cancers in an effort to establish targeted treatment, detection, and prevention methods that can be applied before cancers form.
Colorectal Cancer Clues Provided by Polyp Profiles
Investigators identified mutation, expression, and methylation differences in colorectal polyps from individuals with or without colorectal cancer.
Hereditary Colorectal Cancer Syndrome Caused by Recessive Mutations in Mismatch Repair Gene
Researchers identified two cases with biallelic mutations in MSH3 in exome sequences from more than 100 patients with unexplained colorectal adenomatous polyposis.
Colorectal Adenoma Exomes Reveal Precancerous Somatic Mutation
In individuals at risk of colorectal cancer, pre-cancerous adenomas contain somatic mutations affecting known cancer genes and pathways.
Restarting the trial will require the company to raise additional funds before its money runs out this summer.
Aug 22, 2013
May 30, 2013
Apr 21, 2011
Mar 17, 2011
Mar 3, 2011
Nov 18, 2010
Nov 4, 2010
Oct 28, 2010
Apr 15, 2010
Dec 10, 2009
Feb 12, 2009