In PNAS this week: role for metabolomics in personalized medicine, vaginal microbiome shift linked to preterm birth, and more.
In Nature this week: recurrent non-coding region mutations in chronic lymphocytic leukemia, sequencing study of Barrett's esophagus, and more.
Independent research teams used exome or genome sequencing to compare mutation patterns in matched Barrett's esophagus, esophageal cancer, and normal samples.
While analyzing paired-end sequencing data from esophageal cancer, University of Cambridge researchers uncovered a host of mobile element insertions in the tumors.
Mutations present in tissue from Barrett's esophagus may help predict progression to high-grade dysplasia or cancer.
Researchers identified three esophageal squamous cell carcinoma mutational signatures with genome or exome sequencing.
Survey results reflect strong penetration of Castle Biosciences' uveal melanoma test among specialists as the company plans a future focus on more prevalent diseases.
Caprion, Asuragen, and the AIT Austrian Institute of Technology join the consortium launched in 2013 to develop blood-based tests for the early detection of cancers.
NEW YORK (GenomeWeb) – Cancer molecular diagnostics firm Castle Biosciences today said that it raised $11.8 million in a Series E financing round.
NEW YORK (GenomeWeb News) – A new company spun out of the National University of Singapore (NUS) launched today with a technology that it said can instantly provide a diagnosis for gastric and esophageal cancers during endoscopy.
Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.
Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.
Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.
In PLOS this week: mechanisms for genes implicated in coronary artery disease, rumen microbes and host genetics influence cow methane production, and more.