With genome sequencing, investigators tracked down a sole stool donor carrying the same multi-drug resistant form of Escherichia coli found in two FMT recipients with bacteremia.
In Genome Research this week: PeCanPIE platform for finding, annotating, and ranking pathogenic variants; commensal Escherichia coli analysis; and more.
Based on sequences for hundreds of E. coli ST131 lineage isolates, researchers propose a model that involves negative frequency-dependent selection on accessory parts of the genome.
The nucleic acid diagnostic platform they are developing doesn't require expensive optics, and it could be available as a manufacturing prototype in about a year.
Using meat and clinical samples collected prospectively over a year, researchers found evidence for poultry-to-human transmission of Escherichia coli sequence type 131.
In Science this week: approach to measure microRNA targeting efficiency, strategy to conduct high-throughput chemical screens at single-cell resolution, and more.
