In a retrospective cohort study of Lynch syndrome patients, researchers found that cancer onset varied both by which gene was mutated and how it was altered.
Investigators identified new recurrently mutated genes and overlap with other histological endometrial cancer subtypes by profiling more than a dozen CCEC cases.
MethylCap-seq data for dozens of primary endometrioid endometrial cancers led to a 13-region methylation signature linked to broader tumor genome features.
A team from Mount Sinai and Swift Biosciences used targeted sequencing to detect cancer mutations in uterine lavage fluid.
Two separate studies concluded that in most SEO cancer cases what they are seeing are two separate early-stage tumors, instead of late-stage cancer.
The SBIR grant could be worth as much as $2.3 million and will help PapGene develop and commercialize its proprietary ovarian and endometrial cancer detection test.
Teams tracked immune cell infiltration, PD-L1 expression, and more in tumors from BRCA1/2-mutated ovarian cancers or mutation-rich endometrial cancer subtypes.
The goal is to design personalized noninvasive ddPCR-based panels to monitor ctDNA levels throughout a patient's disease.
Johns Hopkins researchers are using sequencing to detect cancer mutations in cell-free DNA from vaginal fluids collected in tampons.
NEW YORK (GenomeWeb) – OvaGene and Indian life sciences firm iLife Discoveries today announced an alliance to bring gene-based assays targeting ovarian, endometrial, and cervical cancer to India.
Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.
The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.
Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.
In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.