A phylogenetic analysis that included multiple samples per patient suggests overlapping driver mutations make their way into multiple metastases in each patient.
With genotyping data for more than 100,000 endometrial cancer cases and controls, researchers found nine new risk loci before delving into genes and pathways involved.
A team of researchers in Japan used a noninvasive prenatal testing platform to detect copy number alterations in about 20 percent of gynecological cancers they tested.
Partnering with researchers at McGill University, the Johns Hopkins team that developed the method has now demonstrated its power in a much larger group of patients.
In a retrospective cohort study of Lynch syndrome patients, researchers found that cancer onset varied both by which gene was mutated and how it was altered.
Investigators identified new recurrently mutated genes and overlap with other histological endometrial cancer subtypes by profiling more than a dozen CCEC cases.
MethylCap-seq data for dozens of primary endometrioid endometrial cancers led to a 13-region methylation signature linked to broader tumor genome features.
A team from Mount Sinai and Swift Biosciences used targeted sequencing to detect cancer mutations in uterine lavage fluid.
Two separate studies concluded that in most SEO cancer cases what they are seeing are two separate early-stage tumors, instead of late-stage cancer.
The SBIR grant could be worth as much as $2.3 million and will help PapGene develop and commercialize its proprietary ovarian and endometrial cancer detection test.
An Australian-led team has generated a draft genome assembly of the invasive cane toad in hopes it will help in population control, the Sydney Morning Herald reports.
The New York Times reports that the US Department of Defense has implemented about half the recommendations made to improve safe handling of dangerous agents.
In PLOS this week: approach for teasing out archaic introgression in human genomes, immune transcription features in HCV infection, and more.
Stat News reports that Maryland is promoting itself to the biotech industry with a mobile billboard.