At Tri-Con, UCSF's Charles Chiu discussed validation of a metagenomic NGS test as well as a new project to develop an RNA sequencing panel for Lyme disease.

The study involved 11 sites and 1,560 prospectively collected patient samples and demonstrated high overall positive and negative percent agreement with comparator assays.

Oh, Put That Anywhere

A Centers for Disease Control and Prevention-operated lab had its permit for working with dangerous pathogens suspended due to safety violations, USA Today reports.

The high-throughput system is now approved with the firm's Blood Culture ID, Gastrointestinal, Meningitis/Encephalitis, and the previously approved Respiratory Panel. 

Researchers sequenced and analyzed the negative-sense RNA tilapia lake virus, implicated in large die-offs of farmed and wild tilapia in Israel and Ecuador.

The FilmArray ME Panel received a de novo clearance from the US Food and Drug Administration in October.

The FilmArray ME Panel is the first nucleic acid amplification test to detect multiple pathogens from a single cerebrospinal fluid sample. 

The US Centers for Disease Control and Prevention is investigating the handling of samples at four Department of Defense labs, the New York Times reports.

The UCSF Center for Next-Gen Precision Medicine Diagnostics will use NGS to develop technology to diagnose meningitis and encephalitis. 

variegated squirrel

Sequence and other data suggest a squirrel-borne bornavirus may be behind three mysterious deaths in Germany.


Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.

The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.

Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.