The prospective, multi-site clinical trial will evaluate the clinical utility of unbiased sequencing for identifying pathogens in suspected CNS infections.
At Tri-Con, UCSF's Charles Chiu discussed validation of a metagenomic NGS test as well as a new project to develop an RNA sequencing panel for Lyme disease.
The study involved 11 sites and 1,560 prospectively collected patient samples and demonstrated high overall positive and negative percent agreement with comparator assays.
A Centers for Disease Control and Prevention-operated lab had its permit for working with dangerous pathogens suspended due to safety violations, USA Today reports.
The high-throughput system is now approved with the firm's Blood Culture ID, Gastrointestinal, Meningitis/Encephalitis, and the previously approved Respiratory Panel.
Researchers sequenced and analyzed the negative-sense RNA tilapia lake virus, implicated in large die-offs of farmed and wild tilapia in Israel and Ecuador.
The FilmArray ME Panel received a de novo clearance from the US Food and Drug Administration in October.
The FilmArray ME Panel is the first nucleic acid amplification test to detect multiple pathogens from a single cerebrospinal fluid sample.
The US Centers for Disease Control and Prevention is investigating the handling of samples at four Department of Defense labs, the New York Times reports.
The UCSF Center for Next-Gen Precision Medicine Diagnostics will use NGS to develop technology to diagnose meningitis and encephalitis.
Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.
A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.
An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.
In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.