Ebola

NEW YORK (GenomeWeb) – Host genetics appear to play a role in response to Ebola virus infection, researchers reported in a paper appearing online in Science today.

NEW YORK (GenomeWeb) — With a new technique to embed and freeze-dry genetic networks in paper, researchers from the Wyss Institute at Harvard University have taken the first steps toward moving a range of molecular diagnostics that currently rely on more complex technologies into a just-add-water

NEW YORK (GenomeWeb) – BioFire Defense, a BioMérieux company, has been granted Emergency Use Authorization by the US Food and Drug Administration for BioThreat-E, a commercially available Ebola molecular diagnostic test for use in CLIA moderate- and high-complexity laboratories.

NEW YORK (GenomeWeb) — BioMérieux yesterday reported approximately 4 percent organic revenue growth for the first nine months of 2014, driven by organic growth in all of its clinical application areas but particularly in molecular biology and immunoassays.

NEW YORK (GenomeWeb) – Using fever to screen for Ebola casts a wide net, while standard RT-PCR requires many hours and expert technicians.

NEW YORK (GenomeWeb) — Cepheid said last week that its third quarter revenues grew 15 percent year over year driven primarily by stronger than expected commercial clinical revenue resulting from new Xpert assays and customer types.

NEW YORK (GenomeWeb) — Tekmira Pharmaceuticals this week announced that it has started limited manufacturing of a new version of its siRNA Ebola treatment TKM-Ebola to specifically target the Guinea variant of the disease that is responsible for the current outbreak in Africa.

A majority of these assays use standard RT-PCR, but a few have novel methodologies that may help control the current outbreak in Africa, prevent an outbreak in the US, and possibly advance the field of molecular diagnostics.

NEW YORK (GenomeWeb) – Swiss-based pathogen sequencing analysis firm BioInnovation Solutions today said that it and the US Army Medical Research Institute of Infectious Diseases have developed a panel for the rapid detection and surveillance of filoviruses, such as Ebola and Marburg.

NEW YORK (GenomeWeb) – Tekmira Pharmaceuticals this week announced that it has received clearance from the US Food and Drug Administration to provide its experimental Ebola drug, called TKM-Ebola, to individuals with confirmed or suspected infections under expanded access protocols.

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NPR reports that with medical data being big business, some companies want to get patients involved.

The Asbury Park Press reports on the startup Genomic Prediction's test to determine an embryo's risk of disease.

In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.

Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.